[Translation] A Phase III long-term extension study evaluating the safety and efficacy of Imsidolimab (ANB019) in adult subjects with generalized pustular psoriasis
主要目的是评估imsidolimab在参与ANB019-301研究的GPP受试者中的长期安全性。
次要目的是评估imsidolimab在参与ANB019-301研究的GPP受试者中的长期疗效。
探索性目的是评估imsidolimab在GPP受试者中的PK;评估imsidolimab的免疫原性;进行药物遗传学分析;在ANB019-301研究第1天并发斑块型银屑病的受试者中评估imsidolimab对斑块型银屑病的影响。
[Translation] The primary objective is to evaluate the long-term safety of imsidolimab in GPP subjects participating in the ANB019-301 study.
The secondary objective is to evaluate the long-term efficacy of imsidolimab in GPP subjects participating in the ANB019-301 study.
The exploratory objectives are to evaluate the PK of imsidolimab in GPP subjects; evaluate the immunogenicity of imsidolimab; perform pharmacogenetic analysis; and evaluate the effect of imsidolimab on plaque psoriasis in subjects with concurrent plaque psoriasis on Day 1 of the ANB019-301 study.