Delving into the Latest Updates on Jilin Huakang Pharmaceutical Co. Ltd. with Synapse

Overview

Tags

Urogenital Diseases

Cardiovascular Diseases

Nervous System Diseases

Herbal medicine

Small molecule drug

Disease domain score

A glimpse into the focused therapeutic areas

Technology Platform

Most used technologies in drug development

Targets

Most frequently developed targets

Disease Domain	Count

Nervous System Diseases	2
Neoplasms	1

Top 5 Drug Type	Count

Small molecule drug	2
Herbal medicine	2

Top 5 Target	Count

VDCCs(Voltage-gated calcium channel)	1

评价局部注射复方硫酸铝注射液对比TURBT术治疗非肌层浸润性膀胱癌(Ta/T1期)或良性膀胱肿瘤的安全性和有效性。这是一个多中心、随机、开放、平行、非劣效的试验设计。主要关注TURBT手术和复方硫酸铝注射在第三年的复发率的比较。

[Translation]

To evaluate the safety and efficacy of local injection of aluminum sulfate compound injection compared with TURBT for the treatment of non-muscle invasive bladder cancer (Ta/T1 stage) or benign bladder tumors. This is a multicenter, randomized, open, parallel, non-inferiority trial design. The main focus is on the comparison of the recurrence rate between TURBT surgery and aluminum sulfate compound injection in the third year.

Start Date13 Dec 2017

Sponsor / Collaborator

Chinese People's Liberation Army General Hospital

[+1]

CTR20160209

/ RecruitingPhase 3

银花泌炎灵片治疗Ⅲ型前列腺炎（湿热下注证）的随机、双盲、阳性药及安慰剂平行对照、多中心临床试验

[Translation] A randomized, double-blind, positive drug and placebo-controlled, multicenter clinical trial of Yinhua Miyanling Tablets in the treatment of type III prostatitis (damp-heat syndrome)

以阳性药及安慰剂为对照，进一步评价银花泌炎灵片治疗Ⅲ型前列腺炎（湿热下注证）的有效性与安全性，为产品的注册申请提供依据。

[Translation]

Using the positive drug and placebo as controls, the efficacy and safety of Yinhua Miyanling Tablets in the treatment of type III prostatitis (syndrome of damp-heat invasion) were further evaluated to provide a basis for the product registration application.

Start Date24 Aug 2016

Sponsor / Collaborator

Jilin Huakang Pharmaceutical Co. Ltd.

100 Clinical Results associated with Jilin Huakang Pharmaceutical Co. Ltd.

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0 Patents (Medical) associated with Jilin Huakang Pharmaceutical Co. Ltd.

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10

Literatures (Medical) associated with Jilin Huakang Pharmaceutical Co. Ltd.

Zhongguo Xiandai Zhongyao

HPLC determination of tanshinone II_A in Xueshuanxinmaining capsule

Author: Yu, Yongjia ; Li, Xiujuan ; Li, Zhenwei

A method for HPLC determination of Tanshinone II_A in Xueshuanxinmaining capsule was established.The condition for HPLC was ZORBAX SB-C₁₈ column (4.6 mm × 250 mm, 5 μm) with methanol-water-acetic acid (75:24:1) as the mobile phase.The flow rate was 1.0 mL/min^-1 and the detection wavelength was 270 nm.The standard curve was liner in the range of 3.44-55.04 μg and the correlation coefficient was 0.999 2.The coverage recovery was 98.67% with RSD 0.28%.The method shows good separating result, accuracy and reproducibility, can be used for the quality control of Xueshuanxinmaining capsule.

Zhongguo Xiandai Zhongyao

Determination of berberine hydrochloride and paeoniflorin in qingweizhitong pellet by HPLC

Author: Zhang, Dan ; Li, Sheng ; Dong, Changping ; Wang, Zhaohua ; Liu, Chuangui

The purpose of the research is to determine the content of berberine hydrochloride and paeoniflorin in Qingweizhitong pellet by high performance liquid chromatog. in different conditions.The determination for berberine hydrochloride was conducted by Diamonsil-C₁₈ column(250 mm*4.6 mm, 5μm), the mobile phase was acetonitrile-0.033 mol·L^-1 potassium dihydrogen phosphate(30:70 for volume), the detection wavelength was 345 nm.The determination for paeoniflorin was conducted by Shimpack C₁₈(150 mm*4.6 mm, 5 μm), the mobile phase was acetonitrile -0.3% phosphoric acid(12.7:87.3 for volume), the detection wavelength was 230 nm.Good linear relationship between area and amount was noted in the range of 0.016-0.080 μg for berberine hydrochloride with a correlation coefficient of 0.9998.The average recovery of berberine hydrochloride was 98.68%, and the RSD was 0.74%.Good linear relationship between area and amount was noted for 0.268-1.340 μg for paeoniflorin with a correlation coefficient of 0.9999.The average recovery of paeoniflorin was 99.03%, and the RSD was 0.79%.The established method is simple, accurate, sensitive and good repeatability, which can be applied for the quality control of Qingweizhitong pellet.

Zhongguo Xiandai Zhongyao

Determination of Salvia miltiorrhiza Bge. in Shexiang Xinnaotong tablet by HPLC

Author: Bi, Mingyan ; Fu, Xiaodong ; Wu, Meixian

The objective of this paper is to establish the method for high performance liquid chromatog. determination of danshensu sodium in Shexiangxinnaotong tablet.The condition for high performance liquid chromatog. was Shim-pack C₁₈ column (150 mm × 4.6 mm, 5 μm) with methanol-[water, DMF, glacial acetic acid (93:2:1)] (11.7:88.3) as the mobile phase.The flow rate was 1 mL/min^-1 and the detection wavelength was 283 nm.The results showed that the standard curve was liner in the range of 0.516-2.58 μg and the correlation coefficient was 0.999 6.The average recovery was 98.8% with relative standard deviation 0.73%.It was concluded that the method shows good separating result, accuracy, reproducibility, and can be used for the quality control of Shexiangxinnaotong tablet.

100 Deals associated with Jilin Huakang Pharmaceutical Co. Ltd.

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100 Translational Medicine associated with Jilin Huakang Pharmaceutical Co. Ltd.

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Pipeline

Pipeline Snapshot as of 09 May 2025

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

Phase 2 Clinical

1

Phase 3 Clinical

Approved

2

Other

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Current Projects

Drug(Targets)	Indications	Global Highest Phase

Yinhua Miyanling Tablets	Pyelonephritis More	Approved
Xueshuanxinmaining tablet	Brain Infarction More	Approved
Compound aluminum sulfate	Transitional Cell Carcinoma More	Phase 3
Pseudo-Ginsenoside GQ ( VDCCs )	Angina, Stable More	Phase 2
PDQ	Arrhythmias, Cardiac More	Pending