Delving into the Latest Updates on Ihara Chemical Industry Co., Ltd. with Synapse

Overview

Pyroxasulfone, which was discovered and developed by K-I Chemical Research Institute Co., Ltd.; Kumiai Chemical Industry Co., Ltd.; and Ihara Chemical Industry Co., Ltd., is a novel pre-emergence herbicide for wheat, corn, and soybean. Pyroxasulfone inhibits the biosynthesis of very-long-chain fatty acids in plants and has shown excellent herbicidal activity against grass and broadleaf weeds at lower application rates compared with other commercial herbicides. This pesticide has been registered in Japan, Australia, the USA, Canada, Saudi Arabia, and South Africa, and we sell pyroxasulfone products through domestic partner companies in each of these countries. With its high efficacy and relatively low application rates, we believe that pyroxasulfone will contribute to efficient global food production in the future.

01 Jan 2016·Japanese Journal of Pesticide Science

Development of the novel pre-emergence herbicide pyroxasulfone

Author: Uchida, Yukio ; Nakatani, Masao ; Honda, Hisashi ; Yamaji, Yoshihiro

18 Sep 2015·The Journal of Organic ChemistryQ2 · CHEMISTRY

Series of Carbazole–Pyrimidine Conjugates: Syntheses and Electronic, Photophysical, and Electrochemical Properties

Q2 · CHEMISTRY

Article

Author: Hiyoshi, Hidetaka ; Kato, Shin-ichiro ; Umezu, Kazuto ; Nakamura, Yosuke ; Yamada, Yuji

A series of carbazole-pyrimidine conjugates 1-17 were synthesized by Pd-catalyzed cross-coupling, oxidation, and nucleophilic aromatic substitution reactions. In 1-17, the carbazole moieties are connected at the 4,6-positions of the pyrimidine ring either directly or via ethynylene or vinylene spacers, and various electron-donating or electron-withdrawing substituents are introduced at the 2-position of the pyrimidine ring. The effects of structural variations on the electronic, photophysical, and electrochemical properties of 1-17 were comprehensively investigated. Compounds 1-17 exhibit intramolecular charge-transfer (ICT) states, which essentially lead to moderate-to-strong fluorescence emission with large Stokes shifts depending on the solvent polarity. These compounds tend to show significant changes in optical and fluorescence properties upon addition of trifluoroacetic acid. The electron-accepting ability of these compounds can be tuned by both substituents on the pyrimidine moiety and spacers. The ethynylene spacer lowers both the HOMO and LUMO levels, while the vinylene spacer elevates the HOMO level and lowers the LUMO level. The X-ray crystal structures of 3, 6, 11, and 14 are also disclosed.

100 Deals associated with Ihara Chemical Industry Co., Ltd.

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Pipeline

Pipeline Snapshot as of 14 Nov 2024

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

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