[Translation] A multicenter, randomized, double-blind, placebo-controlled phase II clinical study evaluating the efficacy and safety of different doses of naltrexone implants in the treatment of patients with alcohol use disorder
1.主要目的
评价纳曲酮植入剂治疗酒精使用障碍患者的有效性,并进行剂量探索。
2.次要目的
评估纳曲酮植入剂治疗酒精使用障碍患者的安全性。
3.探索性目的
探索纳曲酮植入剂对酒精使用障碍相关的生物学标志物的影响。
[Translation] 1. Main purpose
To evaluate the efficacy and dose-finding of naltrexone implants in patients with alcohol use disorder.
2. Secondary purpose
To assess the safety of naltrexone implants in patients with alcohol use disorder.
3. Exploratory purpose
Exploring the effect of naltrexone implants on biomarkers associated with alcohol use disorder.