Silexion Therapeutics Ltd.

LONDON--( BUSINESS WIRE )-- Silexion Therapeutics (NASDAQ: SLXN) has emerged an intriguing yet under the radar player in the precision oncology space, focusing on developing innovative RNA interference (RNAi) therapies for KRAS-driven cancers. As a recently de-SPACed company following its merger with Moringa Acquisition Corp (NASDAQ: MACA), Silexion presents an interesting opportunity in the rapidly growing field of targeted cancer treatments, particularly in addressing the challenges of pancreatic and potentially other KRAS-driven cancers. Technology Deep Dive: LODER™ and SIL-204 At the core of Silexion's approach is its proprietary LODER™ (Local Drug EluteR) platform, which has demonstrated encouraging results in Phase 2 clinical trials for locally advanced pancreatic cancer. The company's technology stands out due to two key pharmacological functions: oncogene silencing and localized delivery. Silexion's siRNA actively prevents cells from producing oncogenic proteins, contrasting with small molecule KRAS inhibitors that target already-oncogenic proteins. Additionally, the LODER™ system bypasses the tumor barrier, allowing for higher concentrations of treatment directly within the tumor, enhancing efficacy while reducing systemic side effects. Silexion's second-generation improved product, SIL-204, is an optimized siRNA formulation expected to enter Phase 2/3 clinical trials in 2025-2026. SIL-204 represents a significant advancement in RNAi technology, with the potential to target a broader range of KRAS mutations (pan KRAS G12x). This is particularly important as it addresses a wider spectrum of KRAS-driven cancers compared to current small molecule KRAS inhibitors, which are limited to targeting KRAS G12C (found in only 1-2% of pancreatic cancer cases). The Context: The Challenges in Treating Pancreatic Cancer Pancreatic cancer remains one of the most challenging malignancies to treat, with a dismal five-year survival rate of just 12.8%. Several factors contribute to the difficulty in treating this aggressive cancer. Late detection is a major issue, as pancreatic cancer is often diagnosed at advanced stages due to a lack of early symptoms and effective screening methods. The aggressive nature of pancreatic tumors, characterized by rapid growth and early metastasis, further complicates treatment efforts. The dense tumor microenvironment of pancreatic cancer creates a significant barrier to drug penetration, reducing the effectiveness of traditional chemotherapies. Additionally, the genetic complexity of pancreatic cancer, with KRAS mutations present in over 90% of cases, has proven difficult to target effectively with conventional therapies. Compounding these challenges is the tendency of pancreatic cancer cells to develop resistance to standard chemotherapies, leading to poor long-term outcomes. Silexion's LODER™ and SIL-204 technologies are designed to address these challenges directly. By silencing KRAS mutations at the genetic level and delivering treatment locally, Silexion's approach has the potential to overcome the barriers that have historically limited the effectiveness of pancreatic cancer treatments. Clinical Progress and Future Potential Silexion's LODER™ technology has already shown promising results in Phase 2 clinical trials for locally advanced pancreatic cancer. Key findings include a 9.3-month improvement in overall survival when LODER™ was combined with standard chemotherapy, compared to chemotherapy alone in patients with non-resectable pancreatic cancer harboring KRAS G12D/V mutations. The study also revealed an increased objective response rate (ORR) of 55% with LODER™ plus chemotherapy, compared to 20% for standard chemotherapy alone. Notably, the ORR increased to 64% when considering tumors that were initially non-resectable becoming resectable. These results are particularly encouraging given the historically poor outcomes in pancreatic cancer treatment. As SIL-204 moves into Phase 2/3 trials, there is potential for even greater efficacy due to its optimized formulation and broader targeting of KRAS mutation. Expanding Beyond Pancreatic Cancer: Treating Other KRAS-Driven Cancers While Silexion's initial focus has been on pancreatic cancer, the company's innovative RNAi technology and LODER™ platform have significant potential for application in other KRAS-driven cancers. This broader applicability could substantially expand Silexion's market opportunity and impact in the field of precision oncology. The company's pipeline includes plans to target additional types of pancreatic cancer as well as other cancers driven by KRAS mutations. One notable area of potential expansion is colorectal cancer, which is often associated with KRAS mutations and represents a significant unmet medical need. The ability of Silexion's technology to target a broader range of KRAS mutations (pan KRAS G12x) compared to current small molecule inhibitors positions the company favorably for addressing multiple cancer types. This versatility could prove particularly valuable as KRAS mutations are found in various cancers beyond pancreatic, including lung and colorectal cancers. Moreover, the localized delivery system of the LODER™ platform could potentially be adapted for use in other solid tumors, offering a unique advantage in treating cancers that are challenging to target with systemic therapies. This adaptability could open up new avenues for Silexion in treating a wider array of difficult-to-treat cancers. As Silexion advances its clinical trials and potentially expands into these additional indications, it could significantly broaden its addressable market. This expansion potential not only enhances the company's value proposition but also aligns with the growing trend in precision medicine towards developing versatile platforms that can address multiple cancer types driven by similar genetic mutations. Market Potential: Big Pharma's Growing Appetite for Precision Oncology The precision medicine market, particularly in oncology, is experiencing explosive growth, with major pharmaceutical companies like Pfizer aggressively seeking innovative assets to bolster their pipelines. This trend is driven by the projected expansion of the global precision medicine market from $102.17 billion in 2024 to a staggering $470.53 billion by 2034, growing at a CAGR of 16.5%. Within this broader market, KRAS-driven cancers represent a substantial unmet need, with the market for KRAS inhibitors expected to grow at an impressive 36% CAGR, reaching $10 billion by 2032. This rapid growth has sparked a flurry of M&A activity in the precision oncology space, as exemplified by several high-profile acquisitions. For example , Pfizer's landmark $43 billion acquisition of Seagen in 2023, which doubled Pfizer's oncology pipeline and highlighted the growing importance of antibody-drug conjugates (ADCs) and precision oncology treatments. Similarly, AbbVie's $10.1 billion purchase of Immunogen, following the FDA approval of Elahere, a targeted therapy for ovarian cancer, demonstrating the high value placed on innovative, precision-targeted treatments. These deals underscore the willingness of big pharma to invest heavily in cutting-edge oncology assets, particularly those addressing difficult-to-treat cancers with novel approaches. Silexion's focus on RNAi technology for KRAS-driven cancers, especially its innovative approach to pancreatic cancer treatment, positions it as a potentially attractive acquisition target in this landscape. The company's technologies, which have shown initial promising results in clinical trials, seem to align well with the industry trend towards more targeted and personalized cancer therapies. As large pharmaceutical companies continue to seek differentiated assets to fill gaps in their oncology portfolios, Silexion's unique technology and focus on high-unmet-need cancers could make it a valuable addition to a larger company's pipeline. Moreover, with major pharmaceutical companies collectively holding over $170 billion in cash reserves, according to recent reports , the M&A environment seems highly favourable for innovative companies like Silexion. This trend, combined with Silexion's potential to address the challenges of pancreatic cancer - a disease with a dismal five-year survival rate of just 12.8% - positions the company at the intersection of high market demand and critical unmet medical need. Looking Ahead Silexion Therapeutics represents a unique approach in the fight against KRAS-driven cancers, particularly pancreatic cancer. Its innovative RNAi technology, delivered via the LODER™ platform and the promising SIL-204, seems to address many of the challenges that have historically limited progress in treating these aggressive cancers. As the company advances its clinical trials and potentially potential eyes other KRAS-driven cancers, it stands at the forefront of a new era in precision oncology. While the road ahead in drug development is always challenging, Silexion's progress to date and the potential of its technology make it a company to watch in the evolving landscape of cancer treatment. As with any early-stage biotech company, potential stakeholders should conduct thorough due diligence, considering both the promising technology and market opportunity alongside the inherent risks in drug development. PESG Research is a digital research and coverage brand, offering commentary and exploration into the current and future state of the Pharma, BioTech and Sustainability and other industries. * * * This report is for informational purposes only and is not intended to serve as medical financial, investment or any form of professional advice, recommendation or endorsement. Please review the full documentation detailing financial compensation disclosures and disclaimers the text is subject to. PESG Research is a digital brand that has been compensated to publish and syndicate commentary and exploration into innovative companies and industries and it is subject to conflicts of interest as detailed in the full documentation. [ https://justpaste.it/ab9dn/pdf ] www.pesgresearch.com

The deal furthers AstraZeneca’s long-standing interest in KRAS AstraZeneca’s business development team has landed another asset in its new favorite hunting grounds. Partnering with a Chinese biotech once again, the Anglo-Swedish drugmaker has secured a spot in the congested KRAS G12D space in exchange for $24 million upfront. The deal gives AstraZeneca a global license to UA022, a small molecule inhibitor of the once-undruggable oncogene that was in preclinical development at Usynova. The Chinese biotech discovered and advanced the molecule in collaboration with partners including WuXi AppTec, before deciding that AstraZeneca’s offer, which includes up to $395 million in milestones, was too good to turn down. Licensing UA022 moves AstraZeneca onto turf occupied by a growing set of rivals. The authorized KRAS drugs, Amgen’s Lumakras and Mirati Therapeutics’ Krazati, target G12C-mutated cancer. Those mutations cover around 14% of all KRAS-driven cancers, while G12D mutations are more common. Multiple drug developers have latched onto the G12D opportunity. Silenseed took a siRNA candidate into phase 2 in 2018, although ClinicalTrials.gov now lists its status as “unknown.” Mirati has an asset in phase 1/2. Astellas, Jiangsu HengRui Medicine and Revolution Medicines are testing G12D candidates in humans too. UA022 is yet to enter the clinic. The deal furthers AstraZeneca’s long-standing interest in KRAS. In 2012, the drug developer licensed an anti-KRAS antisense oligonucleotide, AZD4785, from Ionis. That candidate never progressed past phase 1, with AstraZeneca pulling the plug after wrapping up a trial in 2019, but the company’s research teams continued to work on the target.  After discovering the KRAS G12C inhibitor AZD4625, AstraZeneca tweaked the molecule to generate the clinical candidate AZD4747. AstraZeneca is years behind the leaders in KRAS G12C, but the potential for its molecule to penetrate the central nervous system could offer a point of differentiation.  AstraZeneca’s desire to add a KRAS G12D inhibitor to its pipeline took it to China once again. This year, many of AstraZeneca’s deals have involved Chinese partners, with the drug developer forming pacts with Eccogene, LaNova Medicines and KYM Biosciences.

The prevalence of pancreatic cancer has been rising since the past few years, which prompts the growing demand for treatment options. The increasing prevalence of cancer, the robust pipeline, and the growing research and development activities to develop novel therapies to treat Pancreatic Cancer drive the market. The companies developing the potential therapies in the last stage of development include FibroGen, Eli Lilly and Company, CARsgen Therapeutics, and several others. LAS VEGAS, Jan. 2, 2023 /PRNewswire/ -- DelveInsight's ' Pancreatic Cancer Pipeline Insight – 2022 ' report provides comprehensive global coverage of available, marketed, and pipeline pancreatic cancer therapies in various stages of clinical development, major pharmaceutical companies are working to advance the pipeline space and future growth potential of the pancreatic cancer pipeline domain. Key Takeaways from the Pancreatic Cancer Pipeline Report DelveInsight's pancreatic cancer pipeline report depicts a robust space with 150+ active players working to develop 170+ pipeline therapies for pancreatic cancer treatment. Key pancreatic cancer companies such as FibroGen, Innovent Biologics, CARsgen Therapeutics, Ascentage Pharma, NGM Biopharmaceuticals, TME Pharma AG, Lee's Pharmaceutical Limited, ImmunityBio, Inc., Rgene Corporation, CSPC ZhongQi Pharmaceutical Technology Co., Ltd., CanBas Co. Ltd., Jiangsu HengRui Medicine Co., Ltd., Bristol-Myers Squibb, SynerGene Therapeutics, Inc., AbbVie, Silenseed Ltd, Galera Therapeutics, Inc., Helix BioPharma, Golden Biotechnology Corporation, Eli Lilly and Company, Innovent Biologics (Suzhou) Co. Ltd., Panbela Therapeutics, Inc., GlaxoSmithKline, Chia Tai Tianqing Pharmaceutical Group, Roche, Prestige Biopharma Limited, Everfront Biotech Co., Ltd., XBiotech, Inc., Incyte Corporation, Ability Pharmaceuticals SL, Lokon Pharma, HCW Biologics, Amplia Therapeutics Limited, BioLineRx, Ltd., Taiho Pharmaceutical, Sanofi, Scandion Oncology, Nelum, Celldex Therapeutics, Merus N.V., Seagen Inc., GC Cell Corporation, MetiMedi Pharmaceuticals, Lumicell, Nuvation Bio Inc., ENB Therapeutics, BioNTech SE, Bayer, Genentech, Inc., Rise Biopharmaceuticals, Inc., Prestige Biopharma Limited, iOnctura, Shanghai Unicar-Therapy Bio-medicine Technology, Shanghai Hengrui Pharmaceutical Co., Ltd., Hangzhou Neoantigen Therapeutics Co., Ltd., EUSA Pharma, Inc.,Agenus Inc., Arcus Biosciences, Inc.Amgen, Biomea Fusion, and others are evaluating pancreatic cancer drugs to improve the treatment landscape. Promising pancreatic cancer pipeline therapies in various stages of development include Pamrevlumab, Niraparib, CT041, APG-1387, BNT141, ENB003, NUV-868, MCLA-128, LUM015, tisotumab vedotin, OMT-111, tusamitamab ravtansine, SCO-101, NGM120, CDX-301, NLM-001, TAS 102, Olaptesed pegol, BL-8040, Gimatecan, AMP945, N-803, HCW9218, BLEX 404, delolimogene mupadenorepvec, Mitoxantrone Hydrochloride Liposome injection, ABTL0812, CBP501, Pemigatinib, SHR-1701, Fluzoparib, XB2001, Cabiralizumab, EF-009, SGT-53, ABBV-927, PBP1510, Vemurafenib, siG12D-LODER, Penpulimab, GC4711, GSK2256098, L-DOS47, SBP-101, Antroquinonol, LY3214996, Sintilimab, RP72, PBP1510, IOA-289, U87, MVT-5873, SHR-A1904, iNeo-Vac-P01, iNeo-Vac-P01, TQB2858, Siltuximab, AGEN1423, AB680, AMG 199, BMF-219, and others. In December 2022, Targovax ASA announced that it has entered into a collaboration agreement with The University of Kansas Cancer Center (KU Cancer Center) and Agenus Inc. to run a clinical trial testing mutant RAS vaccine TG01 in combination with PD-1 CPI balstilimab in pancreatic cancer following surgery and standard-of-care (SoC) chemotherapy. In December 2022, Bluestar Genomics, Inc. announced the initiation of the New Onset Diabetes Management for Earlier Detection (NODMED) trial, one of the largest clinical studies in pancreatic cancer to date. The trial will use Bluestar Genomics' proprietary epigenomic methods for the detection of the disease. In December 2022, iOnctura BV, a clinical-stage biotech developing novel cancer therapies, had been granted €17.5 million ($18.6 million) funding from the European Investment Council's (EIC) accelerator program to develop IOA-289 for pancreatic cancer.The EIC's funding consists of a grant of €2.5 million ($2.7 million) and €15 million ($16 million) of equity investment. In December 2022, In the Phase I/II CodeBreaK 100 trial, the KRAS G12C inhibitor sotorasib achieved meaningful anticancer activity with an acceptable safety profile in heavily pretreated patients with KRAS G12C-mutated metastatic pancreatic cancer, according to researchers at The University of Texas MD Anderson Cancer Center. The results of the trial, published in the The New England Journal of Medicine, indicate an objective response rate of 21.1% and a median time-to-response of 1.5 months, with 84% of patients experiencing disease control. Median progression-free survival was 4 months, and overall survival was 6.9 months. In December 2022, Oncolytics Biotech® Inc. announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation to pelareorep in combination with Roche's anti-PD-L1 checkpoint inhibitor atezolizumab, and the chemotherapeutic agents gemcitabine and nab-paclitaxel, for the treatment of advanced/metastatic pancreatic ductal adenocarcinoma (PDAC). This represents pelareorep's second FDA Fast Track designation. In December 2022, RemeGen Co., Ltd. announced that its latest antibody-drug conjugate (ADC), RC118 for injection, has been granted two orphan drug designations (ODD) by the United States Food and Drug Administration (FDA) for gastric cancer (including gastroesophageal junction cancer) and pancreatic cancer. This marks the Company's fourth, having previously been granted ODD twice for Disitamab Vedotin (RC48) and Telitacicept (RC18) earlier this year. In December 2022, Panbela Therapeutics, Inc. announced that the European Medicines Agency (EMA) Committee for Orphan Medicinal Products issued a positive opinion on Panbela's application for orphan designation of ivospemin ( SBP-101) in combination with gemcitabine and nab-Paclitaxel in patients with metastatic pancreatic ductal adenocarcinoma (PDA). In September 2022, Qualigen Therapeutics, Inc. announced the presentation of two posters on QN-302 at the AACR 8th Special Conference on Pancreatic Cancer. The data presented include information on the compound's safety, tolerability, and efficacy in a pancreatic cancer model. The poster included preclinical toxicology data that showed QN-302 does not produce adverse toxicological reactions in mouse models at therapeutic doses. In in vitro tests, QN-302 inhibits acetylcholinesterase (AChE) by 53% and muscarinic receptor (M2) by 70% at 1 µM. Request a sample and discover the recent advances in pancreatic cancer drugs @ Pancreatic Cancer Pipeline Report The pancreatic cancer pipeline report provides detailed profiles of pipeline assets, a comparative analysis of clinical and non-clinical stage pancreatic cancer drugs, inactive and dormant assets, a comprehensive assessment of driving and restraining factors, and an assessment of opportunities and risks in the pancreatic cancer clinical trial landscape. Pancreatic Cancer Overview Pancreatic cancer develops in the pancreas tissues, an abdomen organ located behind the stomach's bottom portion. The pancreas secretes hormones that help control blood sugar and enzymes that aid digestion. Pancreatic cancer is a condition in which malignant (cancer) cells develop in pancreatic tissues. The pancreas can develop tumors in various ways, including malignant and noncancerous tumors. However, the precise causes of pancreatic cancer are unknown. Individuals diagnosed with pancreatic cancer before the tumor develops or spreads have an average life expectancy of pancreatic cancer of 3 to 3.5 years. Pancreatic cancer symptoms may include jaundice, dark urine, weight loss, loss of appetite, fatigue, and others. A pancreatic cancer diagnosis is difficult because symptoms are frequently confused with those of other disorders, such as irritable bowel syndrome. The extent of the cancer determines the treatment of pancreatic cancer options. Pancreatic cancer treatment options may include surgery, chemotherapy, radiation therapy, targeted therapy, or a combination of these. Learn more about the diseases and pancreatic cancer diet @ Pancreatic Cancer Tests A snapshot of the Pancreatic Cancer Pipeline Drugs mentioned in the report: Learn more about the emerging pancreatic cancer treatment options @ Pancreatic Cancer Clinical Trials Pancreatic Cancer Therapeutics Assessment The pancreatic cancer pipeline report proffers an integral view of pancreatic cancer emerging novel therapies segmented by stage, product type, molecule type, mechanism of action, and route of administration. Scope of the Pancreatic Cancer Pipeline Report Coverage: Global Therapeutic Assessment By Product Type: Mono, Combination, Mono/Combination Therapeutic Assessment By Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III Therapeutics Assessment By Route of Administration: Inhalation, Intranasal, Intravenous, Oral, Parenteral, Subcutaneous Therapeutics Assessment By Molecule Type: Antibody, Antisense oligonucleotides, Immunotherapy, Monoclonal antibody, Peptides, Protein, Recombinant protein, Small molecule, Stem Cell, Vaccine Therapeutics Assessment By Mechanism of Action: Connective tissue growth factor inhibitors, Poly(ADP-ribose) polymerase 1 inhibitors, Poly(ADP-ribose) polymerase 2 inhibitors, Immunologic cytotoxicity, T lymphocyte replacements, Growth differentiation factor 15 inhibitors, Endothelin B receptor antagonists, Image enhancers Key Pancreatic Cancer Companies: FibroGen, Innovent Biologics, CARsgen Therapeutics, Ascentage Pharma, NGM Biopharmaceuticals, TME Pharma AG, Lee's Pharmaceutical Limited, ImmunityBio, Inc., Rgene Corporation, CSPC ZhongQi Pharmaceutical Technology Co., Ltd., CanBas Co. Ltd., Jiangsu HengRui Medicine Co., Ltd., Bristol-Myers Squibb, SynerGene Therapeutics, Inc., AbbVie, Silenseed Ltd, Galera Therapeutics, Inc., Helix BioPharma, Golden Biotechnology Corporation, Eli Lilly and Company, Innovent Biologics (Suzhou) Co. Ltd., Panbela Therapeutics, Inc., GlaxoSmithKline, Chia Tai Tianqing Pharmaceutical Group, Roche, Prestige Biopharma Limited, Everfront Biotech Co., Ltd., XBiotech, Inc., Incyte Corporation, Ability Pharmaceuticals SL, Lokon Pharma, HCW Biologics, Amplia Therapeutics Limited, BioLineRx, Ltd., Taiho Pharmaceutical, Sanofi, Scandion Oncology, Nelum, Celldex Therapeutics, Merus N.V., Seagen Inc., GC Cell Corporation, MetiMedi Pharmaceuticals, Lumicell, Nuvation Bio Inc., ENB Therapeutics, BioNTech SE, Bayer, Genentech, Inc., Rise Biopharmaceuticals, Inc., Prestige Biopharma Limited, iOnctura, Shanghai Unicar-Therapy Bio-medicine Technology, Shanghai Hengrui Pharmaceutical Co., Ltd., Hangzhou Neoantigen Therapeutics Co., Ltd., EUSA Pharma, Inc.,Agenus Inc., Arcus Biosciences, Inc., Amgen, Biomea Fusion, and others. Key Pancreatic Cancer Pipeline Therapies: Pamrevlumab, Niraparib, CT041, APG-1387, BNT141, ENB003, NUV-868, MCLA-128, LUM015, tisotumab vedotin, OMT-111, tusamitamab ravtansine, SCO-101, NGM120, CDX-301, NLM-001, TAS 102, Olaptesed pegol, BL-8040, Gimatecan, AMP945, N-803, HCW9218, BLEX 404, delolimogene mupadenorepvec, Mitoxantrone Hydrochloride Liposome injection, ABTL0812, CBP501, Pemigatinib, SHR-1701, Fluzoparib, XB2001, Cabiralizumab, EF-009, SGT-53, ABBV-927, PBP1510, Vemurafenib, siG12D-LODER, Penpulimab, GC4711, GSK2256098, L-DOS47, SBP-101, Antroquinonol, LY3214996, Sintilimab, RP72,PBP1510, IOA-289, U87, MVT-5873, SHR-A1904, iNeo-Vac-P01, iNeo-Vac-P01, TQB2858, Siltuximab, AGEN1423, AB680, AMG 199, BMF-219, and others. Dive deep into rich insights for pancreatic cancer research; visit @ New Treatment for Pancreatic Cancer Table of Contents For further information on pancreatic cancer prevention, reach out @ Pancreatic Cancer Drug Treatment Related Reports Pancreatic Cancer Epidemiology Pancreatic Cancer Epidemiology Forecast – 2032 report delivers an in-depth understanding of the disease, historical, and forecasted pancreatic cancer epidemiology in the 7MM. Pancreatic Cancer Market Pancreatic Cancer Market Insight, Epidemiology, and Market Forecast – 2032 report delivers an in-depth understanding of the market trends, market drivers, market barriers, and key pancreatic cancer companies, including FibroGen, NeoImmuneTech, NOXXON Pharma, Silenseed Ltd., Amgen, NGM Biopharmaceuticals, among others. Advanced Pancreatic Cancer Market Advanced Pancreatic Cancer Market Insight, Epidemiology, and Market Forecast – 2032 report delivers an in-depth understanding of the market trends, market drivers, market barriers, and key advanced pancreatic cancer companies, including AstraZeneca, Merck Sharp & Dohme LLC, Bayer, Roche, among others. Advanced Pancreatic Cancer Pipeline Advanced Pancreatic Cancer Pipeline Insight – 2022 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key advanced pancreatic cancer companies, including FibroGen, NeoImmuneTech, NOXXON Pharma, Silenseed Ltd., Amgen, NGM Biopharmaceuticals, among others. Metastatic Pancreatic Cancer Market Metastatic Pancreatic Cancer Market Insight, Epidemiology, and Market Forecast – 2032 report delivers an in-depth understanding of the market trends, market drivers, market barriers, and key metastatic pancreatic cancer companies, including Takeda Oncology, Salspera, Eli Lilly and Company, among others. Metastatic Pancreatic Cancer Pipeline Metastatic Pancreatic Cancer Pipeline Insight – 2022 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key metastatic pancreatic cancer companies, including Takeda Oncology, Salspera, Eli Lilly and Company, among others. Other Trending Oncology Reports Follicular lymphoma | Indolent lymphoma | Severe Toxicities In Lymphoma | Marginal Zone Lymphoma | Vulvar Squamous Cell Carcinoma | Cholangiocarcinoma | Metastatic Cutaneous Squamous cell Carcinoma | Nasopharyngeal Carcinoma | Ductal Carcinoma in Situ | Oncolytic Virus Cancer Therapy | Cancer Cachexia | Intratumoral Cancer Therapies | Brain Cancer Related Healthcare Blogs Upcoming Oncology Drugs Oncology Market Outlook Future of Oncology Market Related Cases Studies Competitive Intelligence Market Assessment Product Assessment Epidemiology Assessment Related Healthcare Services Healthcare Business Consulting Healthcare Competitive Intelligence Services Healthcare Asset Prioritization Services About DelveInsight DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. Connect with us at LinkedIn Contact Us Shruti Thakur [email protected] +1(919)321-6187 Logo: SOURCE DelveInsight Business Research, LLP