[Translation] Phase Ib clinical trial of safety, tolerability, pharmacokinetics and preliminary pharmacodynamics of SAR107375E injection in Chinese healthy adult subjects with randomized double-blind, placebo-controlled, multiple intravenous bolus injections
主要目的:评估中国健康成年受试者多次静脉推注(推注时间约 10min)SAR107375E 注射液的安全耐受性和人体药代动力学(PK)特征;次要目的:评估 SAR107375E 注射液多次静脉推注的药效学评价指标及特征。
[Translation] Primary objective: To evaluate the safety tolerability and human pharmacokinetic (PK) characteristics of SAR107375E injection by multiple intravenous boluses (bolus injection time of about 10 min) in healthy Chinese adult subjects; Pharmacodynamic evaluation indexes and characteristics of sub-intravenous bolus injection.