[Translation] An open, multicenter Phase I clinical study to evaluate the safety, efficacy, and pharmacokinetic/pharmacodynamic characteristics of SIM1811-03 in patients with advanced tumors
评价SIM1811-03的安全性耐受性和确定后续研究的合适推荐剂量;
评价SIM1811-03治疗晚期实体瘤和皮肤T细胞淋巴瘤(CTCL)的初步疗效
评价SIM1811-03的药代动力学特征和免疫原性;初步评价SIM-1811-03的生物学效应与相关生物标记物的相关性
[Translation] Evaluate the safety and tolerability of SIM1811-03 and determine the appropriate recommended dose for subsequent studies;
Evaluate the preliminary efficacy of SIM1811-03 in the treatment of advanced solid tumors and cutaneous T-cell lymphoma (CTCL)
Evaluate the pharmacokinetic characteristics and immunogenicity of SIM1811-03; Preliminary evaluation of the correlation between the biological effects of SIM-1811-03 and relevant biomarkers