Jiangsu Hechen Pharmaceutical Co., Ltd.

To investigate the pharmacokinetic behavior of the test formulation of ilaprazole enteric-coated tablets and the reference formulation of ilaprazole enteric-coated tablets (Ilian®) in healthy Chinese subjects after single oral administration on an empty stomach or after a meal, and to evaluate the bioequivalence of the two formulations after oral administration on an empty stomach or after a meal. To evaluate the safety of the test formulation of ilaprazole enteric-coated tablets and the reference formulation of ilaprazole enteric-coated tablets (Ilian®) in healthy Chinese subjects after single oral administration on an empty stomach or after a meal.

Study the single oral administration of the test preparation sildenafil citrate oral dissolving film (specification: 50 mg, provided by Zhejiang Heze Pharmaceutical Technology Co., Ltd.) and the reference preparation sildenafil citrate oral administration in fasting and postprandial states. Pharmacokinetics of dissolved film (trade name: Viagra®, specification: 50 mg, licensed by Biotech Co., Ltd.) in healthy adult subjects, and the bioequivalence of the two preparations taken orally on an empty stomach and after a meal was evaluated.

The pharmacokinetic behavior of the test formulation (T) bilastine orally disintegrating tablets (specification: 10 mg; produced and provided by Jiangsu Hechen Pharmaceutical Co., Ltd.) and the reference formulation (R) bilastine orally disintegrating tablets (Bilaxten®, specification: 10 mg; licensed by Menarini International Operations Luxembourg S.A.; provided by Jiangsu Hechen Pharmaceutical Co., Ltd.) after a single oral dose in healthy adult subjects under fasting conditions was studied, and the bioequivalence of the two formulations after oral administration under fasting conditions was evaluated.