Delving into the Latest Updates on Accuredit Therapeutics (Suzhou) Co., Ltd. with Synapse

Overview

Tags

Endocrinology and Metabolic Disease

Cardiovascular Diseases

Other Diseases

Gene editing

Disease domain score

A glimpse into the focused therapeutic areas

Technology Platform

Most used technologies in drug development

Targets

Most frequently developed targets

Disease Domain	Count

Endocrinology and Metabolic Disease	4

Top 5 Drug Type	Count

Gene editing	5

Top 5 Target	Count

TTR(Transthyretin)	1

Primary objective: To evaluate the safety and tolerability of ART001 injection in subjects with transthyretin amyloidosis polyneuropathy (ATTR-PN); Secondary objective: To evaluate the pharmacokinetics (PK), pharmacodynamics (PD), immunogenicity and efficacy of ART001 injection in subjects with ATTR-PN.

Start Date-

Sponsor / Collaborator

Accuredit Therapeutics (Suzhou) Co., Ltd.

CTR20243298 / Not yet recruitingPhase 1/2

ART001注射液治疗转甲状腺素蛋白淀粉样变性心肌病的多中心、开放、单臂I/IIa期临床研究

[Translation] A multicenter, open, single-arm phase I/IIa clinical study of ART001 injection in the treatment of transthyretin amyloid cardiomyopathy

1、主要目的：评估ART001注射液在转甲状腺素蛋白淀粉样变性心肌病（ATTR-CM）受试者中的安全性和耐受性； 2、次要目的：评估ART001注射液在ATTR-CM受试者中的药代动力学（PK）、药效动力学（PD）、免疫原性和疗效。

[Translation]

1. Primary objective: To evaluate the safety and tolerability of ART001 injection in subjects with transthyretin amyloid cardiomyopathy (ATTR-CM); 2. Secondary objective: To evaluate the pharmacokinetics (PK), pharmacodynamics (PD), immunogenicity and efficacy of ART001 injection in subjects with ATTR-CM.

Start Date-

Sponsor / Collaborator

Accuredit Therapeutics (Suzhou) Co., Ltd.

100 Clinical Results associated with Accuredit Therapeutics (Suzhou) Co., Ltd.

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0 Patents (Medical) associated with Accuredit Therapeutics (Suzhou) Co., Ltd.

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100 Deals associated with Accuredit Therapeutics (Suzhou) Co., Ltd.

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100 Translational Medicine associated with Accuredit Therapeutics (Suzhou) Co., Ltd.

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Pipeline

Pipeline Snapshot as of 07 Nov 2024

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

Preclinical

4

1

Phase 2

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Current Projects

Drug(Targets)	Indications	Global Highest Phase

ART-001(Accuredit) ( TTR )	Transthyretin-mediated amyloidosis More	IND Approval
ART009	Metabolic Diseases More	Preclinical
ART003	Genetic Diseases, Inborn More	Preclinical
ART002(Accuredit)	Metabolic Diseases More	Preclinical
ART010(AccurEdit Therapeutics)	Metabolic Diseases More	Preclinical