GI Innovation, Inc.

SEOUL, South Korea, Jan. 22, 2025 /PRNewswire/ -- GI Innovation (KQ:358570) announced that it signed a Memorandum of Understanding (MOU) with LaNova Medicines (LaNova) for the development of GI-102 and ADC pancreatic cancer combination therapy. This MOU was held on January 15th, local time, during JP Morgan Healthcare Conference (San Francisco, USA). Continue Reading From the left, Rhee Byung-geon, Chairman and CEO of GI Innovation, Dr. Crystal Quin, CEO of LaNova Medicines, and Jang Myoung-ho, CSO of GI Innovation. (Source: GI Innovation) The two companies have been conducting combination therapy study of the immuno-oncology drug GI-102 and ADC LM-302 targeting Claudin18.2 and recently observed excellent anticancer activity in a preclinical pancreatic cancer model. Both substances are in the clinical stage. GI-102 has completed phase 1 clinical trial in the US and Korea and can quickly enter phase 2. LM-302 is currently in phase 3 clinical trial for 3L and above gastric cancer in China. Pancreatic cancer has no approved immunotherapy, and the only approved treatment is a chemotherapy cocktail, but its treatment efficacy is low and its toxicity is high. Through this agreement, both companies will conduct clinical trial targeting patients with metastatic pancreatic cancer. Dr. Myoung Ho Jang, CSO said, "We are delighted to be conducting a combination study with LaNova, which is recognized by global pharma companies. LaNova's ADC, which directly destroys tumor cells to increase the response rate, and GI-102, which can enhance immune memory to increase overall survival, are expected to be a combination therapy that can change the pancreatic cancer treatment paradigm." "GI-102 exemplifies GI Innovation's robust R&D capabilities in immunotherapy. We are excited to explore its combination with LaNova's Claudin18.2 ADC, LM-302, which holds the potential to provide a novel therapeutic option for pancreatic cancer patients" Dr. Crystal Qin, LaNova CEO emphasized. About GI Inovation GI Innovation, a KOSDAQ-listed biotech, pioneers fusion protein drugs for cancer and allergies. Since 2017, it secured $230 million through funding rounds, IPO, and licensing deals for preclinical and clinical assets. Leveraging global partnerships for rapid development, the leading programs include immuno-oncology assets GI-101, subcutaneous form GI-102, and anti-allergy asset GI-301, metabolic immuno-oncology asset GI-108 alongside other innovative programs. SOURCE GI Innovation WANT YOUR COMPANY'S NEWS FEATURED ON PRNEWSWIRE.COM? 440k+ Newsrooms & Influencers 9k+ Digital Media Outlets 270k+ Journalists Opted In GET STARTED

Qure.ai nets $65M for foundational AI Qure.ai has raised $65 million in a Series D funding round led by Lightspeed and 360 ONE Asset. The company said it will use its fresh funds to invest more in foundational AI models, as well as acquire complementary startups in medical technology. It will also be used to accelerate its expansion in the United States and other markets. Early this year, the Mumbai-based company obtained two major clearances from the United States Food and Drug Administration: a breakthrough device designation for its tuberculosis screening AI solution, qSpot-TB, and a 510(k) clearance for the lung nodule on the qXR AI-powered chest X-ray software. Mediwhale bags $12M to seek US FDA approval South Korean health diagnostics firm Mediwhale has scored $12 million in a Series A2 funding round led by the Korea Development Bank. The company claims to offer the world's first retina-based solution – called Reti-CVD – that uses AI to assess cardiovascular disease risk. It plans to use its new funds to pursue a US FDA approval for Reti-CVD. The software was reportedly rolled out across the Yonsei University Health System early this year. "We are determined to secure FDA De Novo approval by 2025, with plans to launch our product in the United States shortly thereafter," CEO Kevin Choi said in a statement. Besides securing a regulatory clearance, Mediwhale also seeks to improve its AI further and develop new solutions to predict chronic kidney disease risk. Mediwhale last raised $2 million in a pre-Series A funding round in 2021 and $9 million in a Series A round in 2023. Huawei launches medical imaging AI Huawei recently unveiled a new AI-powered solution for analysing medical images. Called "Medical Technology Digitalization 2.0," the technology enables smart segmentation, detection, and quantitative analysis of medical images using AI with up to 98% accuracy. Huawei claims the solution can shorten disease diagnosis time by 40%, although it has not specified which disease. Additionally, the AI solution can also be applied to ultrasound devices running on the OpenHarmony operating system. The Chinese tech giant worked with several local medical technology companies, including MED Imaging AI, Wanxiang, Beijing DeepWise, and KFBIO, to develop the solution, which has been implemented in such major projects as the Fourth People's Hospital in Shenyang, capital of China’s northeast Liaoning Province. Korean pharma turns to AI for new drug discovery Korean pharmaceutical company GI Innovation is pursuing the application of AI for new drug development. It recently signed a memorandum of understanding with local company i-Divine to develop its core cancer drug pipelines and utilise the latter's AI solution to discover new cancer therapy targets. i-Divine's AI is based on a large language model trained on over a billion patents, papers, and real-time biological data sourced globally. It was previously utilised to analyse the success potential of 16,000 new drug substances, including one of GI Innovation's anti-cancer drug pipelines. MediBuddy adopts Philips' predictive heart AI MediBuddy in India is integrating Philips' heart health monitoring platform into its mobile health application. The AI-based longitudinal triaging solution called HeartPrint tracks and assesses key biomarkers from a person's finger when scanned through their smartphone's camera. These include cardiovascular age, diabetes risk, OSA risk, cardio-respiratory fitness index, heart rate analysis, cardiac index, blood pressure variability, and stress disorder prediction. The AI solution also analyses patterns indicating a person's risk of developing heart disease, overall health deterioration, heart resilience, and short and long-term changes in cardiac function.

SEOUL, South Korea--( BUSINESS WIRE )--The South Korean biotech company GI Innovation announced today that it has signed a clinical trial collaboration and supply agreement with MSD (a tradename of Merck& Co., Inc., Rahway, NJ, USA) to evaluate the combination of GI-102 and MSD’s anti-PD-1 therapy, KEYTRUDA® (pembrolizumab) in patients with immunotherapy-resistant liver cancer, melanoma, and renal cell carcinoma. This agreement marks GI Innovation’s second clinical trial collaboration with MSD, following a previous collaboration for GI-101A. The Phase 2 clinical trial including GI-102 in combination with KEYTRUDA will enroll patients with resistance or non-response to immuno-oncology treatments, leaving them with no further treatment options. GI Innovation is focused on three indications with significant market potential and potential likelihood of success: metastatic liver cancer, melanoma, and renal cell carcinoma. The company has already demonstrated strong anti-cancer efficacy with a 42.9% overall response rate (ORR) in a monotherapy trial of GI-102 in melanoma patients who failed to respond to standard-of-care treatment (3 partial responses out of 7 patients). Complete tumor regression was previously observed in 60% of mice treated with GI-102 monotherapy in a preclinical liver cancer model. Fourteen hospitals in South Korea and world-renowned sites in the U.S. have agreed to join the trial, including the Mayo Clinic (campuses in Rochester, Florida, and Arizona), Cleveland Clinic and Memorial Sloan Kettering Cancer Center. In South Korea, the trial will take place at leading hospitals including Samsung Medical Center, Asan Medical Center, Seoul National University Hospital, Severance Hospital of Yonsei University, and St. Vincent’s Hospital. "We are pleased to enter into another clinical trial collaboration and supply agreement with MSD, a world leader in immuno-oncology. We aim to maximize the therapeutic value of GI-102 by combining it with KEYTRUDA, MSD’s anti-PD-1 therapy”, said Dr Myung-Ho Jang, GI Innovation’s Chief Scientific Officer. KEYTRUDA® is a registered trademark of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway NJ, USA.