The goals of this study is to evaluate the feasibility and the effects of a WhatsApp-assisted prehabilitation for colorectal cancer patients undergoing elective surgery. The main questions are: If the digital prehabilitation is feasible and acceptable by the colorectal cancer patient prior to elective surgery? If this prehabilitation helps to improve the postoperative complications, length of stay, physical activity and psychological well-being for colorectal cancer patients receiving surgery.
Researcher will compare the prehabilitation plus standard care to standard care only to see if the prehabiliation helps the colorectal cancer patients.
Participants will: 1) enrolled in a approximate 4 weeks (3 episodes/ week) prehabilitation program containing educational information of colorectal cancer, dietary advice, exercises training and psychological podcasting. 2) will answer the survey weekly and after surgery. 3) keep the standard care as per department guidelines

Start Date15 Jan 2026

Sponsor / Collaborator

Tseung Kwan O Hospital

[+1]

ChiCTR2500110717

/ Not yet recruitingNot ApplicableIIT

WhatsApp-assisted prehabilitation programme for adult patient undergoing elective colorectal cancer surgery

Start Date10 Sep 2025

Sponsor / Collaborator

The Chinese University of Hong Kong

[+1]

NCT06225765

/ RecruitingNot ApplicableIIT

A Prospective Trial Comparing Transoral Endoscopic Thyroidectomy Vestibular Approach (TOETVA) and Conventional Open Thyroidectomy

To determine if transoral endoscopic thyroidectomy vestibular approach (TOETVA) is a safe and effective procedure compared to traditional open thyroidectomy. Surgical outcomes, patients' satisfaction, voice and swallowing outcomes will be assessed.

Start Date01 Jul 2024

Sponsor / Collaborator

Tseung Kwan O Hospital

100 Clinical Results associated with Tseung Kwan O Hospital

0 Patents (Medical) associated with Tseung Kwan O Hospital

208

Literatures (Medical) associated with Tseung Kwan O Hospital

01 Jan 2026·AMERICAN JOURNAL OF OPHTHALMOLOGY

International Consensuses and Guidelines on the Etiology, Diagnosis and Management of Intraocular Foreign Bodies (IOFBs) by the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO), the Asia-Pacific Vitreo-retina Society (APVRS), and the Academia Retina Internationalis (ARI)

Article

Author: Wong, Daniel H T ; Chen, Haoyu ; Das, Taraprasad ; Mieler, William F ; Lim, Jennifer I ; Yan, Hua ; Lou, Bingsheng ; Lam, Dennis S C ; Caputo, Georges ; Au, Andrea C K ; Li, Kenneth K W ; Justin, Grant A ; Ruamviboonsuk, Paisan ; Zhang, Feng ; Yu, Seung-Young ; Watson, Stephanie ; Lai, Chi-Chun ; Lee, Eun Kyoung ; Choovuthayakorn, Janejit ; Azad, Rajvardhan ; Huang, Xin ; Radke, Nishant V ; Agrawal, Rupesh ; Fong, Kenneth

PURPOSE:

To discuss the critical aspects and establish a consensus among experts regarding intraocular foreign bodies (IOFB) management, and to standardize clinical management for IOFB cases in order to ensure consistent and optimal clinical outcomes.

DESIGN:

A modified Delphi method to reach a consensus among international experts.

METHODS:

An expert panel was formed by the Academy of Asia-Pacific Professors of Ophthalmology (AAPPO), the Asia-Pacific Vitreo-retina Society (APVRS), and the Academia Retina Internationalis (ARI) to identify the controversy and establish consensus and statement on the management of IOFB. The core group of the panel gathered, reviewed, discussed, and formulated the statements. The statements were rated by the expert panel based on a five-point Likert scale (strongly agree, agree, neutral, disagree and strongly disagree). A consensus was reached when at least 75% of the experts voted either "agree" or "strongly agree" for a statement.

RESULTS:

Twenty four international experts from 11 countries/territories participated. Fifty four consensus statements were reviewed in the following 8 sections: diagnostic controversies, ⁠⁠IOFB characterization controversies, management controversies, prophylactic measures controversies, post-extraction management controversies, special population considerations, outcomes assessment controversies, and future directions. The expert panel showed good agreement in all sections. Consensus was reached for 49 out of 54 statements, while the final score was less than 75% for 5 statements.

CONCLUSION:

The strong majority of consensus statements serves as a useful guidance, enabling clinicians to approach IOFB removal in a systemic manner with more confidence and improve patient outcomes. The varying levels of agreement in some statements underscore remaining uncertainties in IOFB clinical management.

26 Dec 2025·Open Forum Infectious Diseases

Regional Adherence to Early Sepsis Management Bundle and Associated Mortality in Hong Kong Between 2009–2018

Article

Author: Wong, Wai Tat ; Chan, Jacky Ka Hing ; Ling, Lowell ; Lee, Anna ; Ling, Steven ; Chang, Lok Ching ; Au, Ka Fai ; Dharmangadan, Manimala ; Chiu, Lok Ching Sandra ; Cowling, Benjamin J ; Li, Katy Hoi Ki ; Fong, Ka Man ; Zhang, Jack Zhenhe ; Wu, Peng ; Yeung, Alwin Wai Tak ; Chan, Chun Hei ; Wu, William Ka Kei ; Man, Man Yee ; Ho, Eunise ; Tang, Michele ; Ng, Pauline Yeung ; Liong, Ting ; Ho, Kwok Ming ; Rhee, Chanu

Abstract:

Background:

Longitudinal data are scarce on sepsis bundle adherence and associated survival at a country or regional level.

Methods:

A population-based electronic health record database was leveraged to determine temporal trends in sepsis bundle adherence (empirical broad-spectrum antibiotic administration, blood culture collection, lactate measurement) on sepsis onset day and antimicrobial resistance (AMR) prevalence. This study included all adult hospitalizations for community-acquired sepsis at 41 publicly funded hospitals in Hong Kong between 2009 and 2018. Generalized estimating equations were used to assess the association between full bundle adherence and its individual elements with hospital mortality.

Results:

Among 421 096 cases of community-acquired sepsis, the full bundle adherence rate increased from 0.2% in 2009 to 1.2% in 2018 (relative +18.9%/y, P < .001), with limited uptake of each element. The relative increase in empirical broad-spectrum antibiotics administration (+9.8%/y [95% CI, 8.3%–11.2%]) was faster than the AMR prevalence (+5.2%/y [95% CI, 3.6%–6.9%]). Full bundle adherence was associated with reduced mortality (adjusted odds ratio [ORadj], 0.75 [95% CI, .65–.86]). Blood culture collection was associated with reduced mortality (ORadj, 0.88 [95% CI, .83–.93]), while lactate measurement was associated only with reduced mortality in septic shock (ORadj, 0.85 [95% CI, .76–.94]). Broad-spectrum antibiotics was associated with reduced mortality (ORadj, 0.73 [95% CI, .56–.96]) when used appropriately in bacteremia from extended-spectrum beta-lactamase pathogens or methicillin-resistant Staphylococcus aureus.

Conclusions:

Basic sepsis care implementation remains challenging even in high-income settings. Empirical broad-spectrum antibiotic usage has outpaced AMR risk. Full sepsis bundle adherence was associated with improved survival, but empirical broad-spectrum antibiotics was associated with better survival only if used appropriately. Efforts should focus not only on ensuring bundle adherence but also on prioritizing the right treatments for the right patients.

01 Oct 2025·RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES

PHYSICAL FACTORS INFLUENCING THE COMPLETENESS OF REMOVAL OF RESIDUAL PERFLUOROCARBON LIQUID IN VITREORETINAL SURGERY

Article

Author: Chen, Ying ; Steel, David H. ; Guo, Wei ; Chu, Wang Yee ; Chan, Yau Kei ; Lau, Chun Wai Maggie ; Long, Zhongdui ; Li, Kenneth Kai Wang

Purpose::

Postoperative perfluorocarbon liquid (PFCL) retention would lead to serious complications, especially retinal toxicity and intraocular inflammation. This study aimed to elucidate the roles of air infusion pressure and residual balanced salt solution in PFCL evaporation during vitreoretinal surgery, thereby optimizing residual PFCL removal, minimizing complications, and improving patient outcomes.

Methods::

Evaporation rates of perfluoro-n-octane and perfluoro-decalin were studied using a 3D-printed eye model under varying air infusion pressures from 10 to 40 mmHg. Computational fluid dynamics simulations were used to qualitatively capture PFCL evaporation dynamics, followed by interpretation with a quantitative mathematical model, which also elucidates the impact of the balanced salt solution film on PFCL evaporation.

Results::

In the 3D-printed eye model, PFCL completely evaporated at rates of 1.03 µL/second (perfluoro-n-octane) and 0.28 µL/second (perfluoro-decalin) at an air pressure of 30 mmHg. Perfluorocarbon liquid evaporation rate increased almost linearly from 10 to 30 mmHg (P < 0.05) before reaching its maximum level. Computational fluid dynamics simulations revealed enhanced PFCL evaporation rate as air pressure rises. A mathematical model, based on inlet air pressure enhanced PFCL vapor diffusion, was derived to quantitatively capture PFCL evaporation under clinical conditions with balanced salt solution.

Conclusion::

Both in vitro experiments and mathematical models indicate that trace amounts of PFCL could evaporate completely under surgically representative air pressure levels without significantly extending surgical time. Inlet air pressure significantly accelerates PFCL vapor diffusion rate, dominating PFCL evaporation. The height of the balanced salt solution film exerts a determinant effect on the evaporation of PFCL even under the surgically relevant air infusion pressure level.

100 Deals associated with Tseung Kwan O Hospital

100 Translational Medicine associated with Tseung Kwan O Hospital

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