评价HBW-004285胶囊在健康受试者中单次/多次给药的安全性、耐受性、药代动力学和药效动力学的I期临床试验
[Translation] Phase I clinical trial to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of single/multiple administration of HBW-004285 capsules in healthy subjects
主要目的: 在健康成年受试者中评估HBW-004285单次给药和多次给药的安全性和耐受性;
次要目的: 在健康成年受试者中分别评估HBW-004285单次给药和多次给药后的药代动力学(PK)特征; 评价食物对HBW-004285单次给药后药代动力学的影响; 初步评价HBW-004285的代谢和排泄特征; 评估HBW-004285对ECG参数的影响。
[Translation] Primary objective: To evaluate the safety and tolerability of HBW-004285 after single and multiple administrations in healthy adult subjects;
Secondary objectives: To evaluate the pharmacokinetic (PK) characteristics of HBW-004285 after single and multiple administrations in healthy adult subjects; To evaluate the effect of food on the pharmacokinetics of HBW-004285 after a single administration; To preliminarily evaluate the metabolism and excretion characteristics of HBW-004285; To evaluate the effect of HBW-004285 on ECG parameters.
100 Clinical Results associated with Shenzhen Haibowei Pharmaceutical Co., Ltd.
0 Patents (Medical) associated with Shenzhen Haibowei Pharmaceutical Co., Ltd.
100 Deals associated with Shenzhen Haibowei Pharmaceutical Co., Ltd.
100 Translational Medicine associated with Shenzhen Haibowei Pharmaceutical Co., Ltd.