[Translation] An open-label, multicenter phase I clinical trial evaluating the safety, tolerability, pharmacokinetic characteristics, immunogenicity, and preliminary efficacy of the personalized neoantigen mRNA vaccine RGL-270 in combination with adebelimab in patients with advanced malignant solid tumors.
评价RGL-270联合阿得贝利单抗在晚期恶性实体瘤患者中的安全性和耐受性,确定RGL-270联合阿得贝利单抗治疗的推荐扩展剂量(RDE)
[Translation] To evaluate the safety and tolerability of RGL-270 in combination with adebenone in patients with advanced malignant solid tumors, and to determine the recommended extended dose (RDE) of RGL-270 in combination with adebenone.