[Translation] A randomized, double-blind, placebo-controlled Phase II clinical trial to evaluate the safety, efficacy, pharmacokinetics and pharmacodynamics of ICP-332 in patients with moderate to severe atopic dermatitis
1.评估ICP-332治疗中重度特应性皮炎(AD)成人受试者的安全性和耐受性。
2.使用湿疹面积和严重程度指数(EASI)评分,评估ICP-332治疗中重度AD的疗效。
3.ICP-332 治疗中重度AD成人受试者其他疗效终点和患者报告的结果。
4.评估ICP-332 在中重度AD成人受试者中的药代动力学(PK)特征。
[Translation] 1. Evaluate the safety and tolerability of ICP-332 in the treatment of adult subjects with moderate to severe atopic dermatitis (AD).
2. Evaluate the efficacy of ICP-332 in the treatment of moderate to severe AD using the Eczema Area and Severity Index (EASI) score.
3. Other efficacy endpoints and patient-reported outcomes of ICP-332 in the treatment of adult subjects with moderate to severe AD.
4. Evaluate the pharmacokinetic (PK) characteristics of ICP-332 in adult subjects with moderate to severe AD.