[Translation] A multicenter, randomized, open-label, active-controlled phase IIb clinical trial evaluating the efficacy and safety of antimicrobial peptide PL-5 spray in the treatment of wound infection
主要目的:以磺胺嘧啶银乳膏为阳性对照,评价抗菌肽PL-5喷雾剂治疗创面感染的有效性和安全性。 次要目的:确认抗菌肽PL-5喷雾剂临床使用的最佳有效剂量,评估抗菌肽PL-5喷雾剂通过创面吸收的药代动力学特征。
[Translation] Main purpose: To evaluate the efficacy and safety of antimicrobial peptide PL-5 spray in the treatment of wound infection with silver sulfadiazine cream as a positive control. Secondary objectives: To confirm the optimal effective dose of antimicrobial peptide PL-5 spray for clinical use, and to evaluate the pharmacokinetics of antimicrobial peptide PL-5 spray absorbed through wounds.