Last update 01 Nov 2024

OPKO IP Holdings II, Inc.

Private Company

Overview

Related

3
Drugs associated with OPKO IP Holdings II, Inc.
Calcifediol
Target
VDR
Mechanism
VDR agonists
Active Org.
Faes Farma SA [+2]
Originator Org.
Organon USA, Inc.
Active Indication
Hyperparathyroidism, Secondary [+1]
Inactive Indication
Bone Cancer [+10]
Drug Highest PhaseApproved
First Approval Ctry. / Loc.
US
First Approval Date05 Aug 1980
Ercalcitriol
Target
VDR
Mechanism
VDR agonists
Active Org.-
Originator Org.
OPKO Health, Inc.OPKO Health, Inc.
Active Indication-
Inactive Indication
Hyperparathyroidism, Secondary [+1]
Drug Highest PhaseDiscontinued
First Approval Ctry. / Loc.-
First Approval Date-
Lunacalcipol
Target
CYP24A1 x VDR
Mechanism
CYP24A1 inhibitors [+1]
Active Org.-
Originator Org.
OPKO Health, Inc.OPKO Health, Inc.
Active Indication-
Inactive Indication
Chronic Kidney Diseases [+4]
Drug Highest PhaseDiscontinued
First Approval Ctry. / Loc.-
First Approval Date-
5
Clinical Trials associated with OPKO IP Holdings II, Inc.
NCT01704079 / CompletedPhase 3
A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate Efficacy and Safety of CTAP101 Capsules to Treat Secondary Hyperparathyroidism in Subjects With Stage 3 or 4 Chronic Kidney Disease and Vitamin D Insufficiency
NCT01651000 / CompletedPhase 3
A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate Efficacy and Safety of CTAP101 Capsules to Treat Secondary Hyperparathyroidism in Subjects With Stage 3 or 4 Chronic Kidney Disease and Vitamin D Insufficiency
NCT00888069 / CompletedPhase 1
A Randomized, Open-Label, Single-Dose Pilot Study of Oral and i.v. CTAP101 Evaluating PK and Safety in Stage 3 and 4 CKD Subjects With Vitamin D Insufficiency and SHPT
100 Clinical Results associated with OPKO IP Holdings II, Inc.
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0 Patents (Medical) associated with OPKO IP Holdings II, Inc.
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100 Deals associated with OPKO IP Holdings II, Inc.
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100 Translational Medicine associated with OPKO IP Holdings II, Inc.
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Pipeline

Pipeline Snapshot as of 27 Dec 2024

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3
Other
3
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Current Projects

Drug(Targets)IndicationsGlobal Highest Phase
Ercalcitriol
 ( VDR )		Kidney Failure, Chronic
More
Pending
Calcifediol
 ( VDR )		Kidney Failure, Chronic
More
Pending
Lunacalcipol
 ( CYP24A1 x VDR )		Kidney Failure, Chronic
More
Pending
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