Allos Therapeutics, Inc.

HAMILTON, ON and BOSTON, Oct. 16, 2023 /PRNewswire/ -- Fusion Pharmaceuticals Inc. (Nasdaq: FUSN), a clinical-stage oncology company focused on developing next-generation radiopharmaceuticals as precision medicines, announced the appointment of Jeremy Bender, Ph.D., M.B.A., Teresa Bitetti, M.B.A., and David Meek to its Board of Directors, effective today. "We are excited to welcome Jeremy, Teresa and David to Fusion's Board of Directors, each bringing an exceptional breadth of experience and track record of success in oncology drug development, business development and commercialization. Their experiences introducing innovative therapies to cancer patients as leaders of top-tier oncology companies will be invaluable as we advance our pipeline, particularly our lead program FPI-2265, which is on track to be the first actinium-based PSMA targeted alpha therapy (TAT) to market," said Fusion Chief Executive Officer John Valliant, Ph.D. "Fusion is undergoing an exciting evolution to a later stage radiopharmaceutical company and with these appointments we are transforming our Board to maximize the value generation of our strategy." Dr. Bender, Ms. Bitetti and Mr. Meek succeed Johan Christenson, Ph.D., Chau Khuong and Heather Preston, M.D., who will step down from Fusion's Board effective today. "I want to thank Johan, Chau and Heather for their significant contributions and unwavering support that enabled Fusion to become a vertically integrated radiopharmaceutical company with a deep clinical-stage pipeline and a proprietary radiopharmaceutical manufacturing facility," Dr. Valliant said. Dr. Jeremy Bender is currently Chief Executive Officer of Day One Biopharmaceuticals, a clinical-stage biopharmaceutical company focused on pediatric cancer. Previously, Dr. Bender served as Vice President of Corporate Development at Gilead Sciences, overseeing acquisitions, partnerships and investments. He also served as Chief Operating Officer at Tizona Therapeutics, Chief Business Officer at Sutro Biopharma, and Vice President of Corporate Development at Allos Therapeutics, and began his career at Boston Consulting Group in the life sciences practice. He currently sits on the Board of Mereo BioPharma as an Independent Board Member. Dr. Bender holds a B.S. in Biological Sciences from Stanford University, a Ph.D. in Microbiology and Immunology from the University of Colorado and an M.B.A. from the MIT Sloan School of Management. Ms. Teresa Bitetti currently serves as President of the Global Oncology Business Unit of Takeda. Previously, Ms. Bitetti held various roles of increasing responsibility at Bristol-Myers Squibb Company (BMS), including as Senior Vice President, Head of Worldwide Oncology Commercialization. At BMS, she also served as Senior Vice President and Head of the U.S. Oncology business, President and General Manager of BMS Canada, and Worldwide Head of the BMS Virology business. Before BMS, Ms. Bitetti also held various roles of increasing responsibility at Mobil Oil Corporation. Ms. Bitetti currently serves on the board of Osmol Therapeutics as an independent director. Ms. Bitetti holds a B.A. from Wellesley College and an M.B.A. from the Darden School of Business at the University of Virginia. Mr. David Meek most recently served as Chief Executive Officer and Member of the Board of Directors of Mirati Therapeutics. Prior to this role, he served as the President, CEO and Board Member of FerGene and CEO and Board Member of Ipsen. Mr. Meek was previously an Executive Vice President and President of Oncology at Baxalta Incorporated in the leadup to the acquisition by Shire and Chief Commercial Officer of Endocyte, and he held executive leadership roles at Novartis Pharmaceuticals Corporation and Novartis Oncology. Mr. Meek has served on the boards of Pharmaceutical Research & Manufacturers of America and European Federation of Pharmaceutical Industries & Associations. He currently serves on the Board of Directors of uniQure N.V. and previously served on the Board of Directors of Entasis Therapeutics (acquired by Innoviva). Mr. Meek holds a B.A. from the University of Cincinnati. About Fusion Fusion Pharmaceuticals is a clinical-stage oncology company focused on developing next-generation radiopharmaceuticals as precision medicines. Fusion connects alpha particle emitting isotopes to various targeting molecules to selectively deliver the alpha emitting payloads to tumors. Fusion's clinical portfolio includes: FPI-2265 targeting prostate specific membrane antigen (PSMA) for metastatic castration resistant prostate cancer currently in a Phase 2 trial; FPI-1434 targeting insulin-like growth factor 1 receptor currently in a Phase 1 trial; and FPI-2059, a small molecule targeting neurotensin receptor 1 (NTSR1), currently in a Phase 1 trial. In addition to a robust proprietary pipeline, Fusion has a collaboration with AstraZeneca to jointly develop novel targeted alpha therapies (TATs) and combination programs between Fusion's TATs and AstraZeneca's DNA Damage Response Inhibitors (DDRis) and immuno-oncology agents. The Company recently received IND clearance for FPI-2068, the first novel TAT under the collaboration, which targets EGFR-cMET. Fusion has also entered into a collaboration with Merck to evaluate FPI-1434 in combination with Merck's KEYTRUDA® (pembrolizumab) in patients with solid tumors expressing IGF-1R. To support Fusion's growing pipeline of TATs, the Company has signed strategic actinium supply agreements with TRIUMF, Niowave, Inc. and BWXT Medical. Contact: Amanda Cray Senior Director of Investor Relations & Corporate Communications (617) 967-0207 [email protected] SOURCE Fusion Pharmaceuticals

EMERYVILLE, Calif.--(BUSINESS WIRE)-- OmniAb, Inc. (NASDAQ: OABI) announces that Director Sunil Patel passed away suddenly last week. The Board of Directors and leadership of OmniAb extend their deepest condolences to those who loved and cared for Sunil and express their gratitude for Sunil’s many contributions to OmniAb. Sunil Patel was appointed to OmniAb’s Board in November 2022 when OmniAb was spun-out of Ligand Pharmaceuticals as an independent, publicly-traded company, and previously served on the Ligand Pharmaceuticals Board of Directors since 2010. “It is with profound sadness that we announce Sunil’s passing,” said John Higgins, OmniAb Board Chair. “Sunil was a highly-valued and engaged member of the OmniAb Board of Directors and played an important role driving our investments and strategy. Above that, he was a friend and colleague for the past two decades. He will be remembered by all who had the pleasure of working with him as a very thoughtful business operator, strongly devoted to cutting-edge science supporting medical research. He was kind and gentle, and an independent thinker who brought levity and joy to any meeting or encounter. Sunil’s support for antibody discovery research and the formation of OmniAb are among his most important business contributions. He saw the future of where the field was going and at every turn helped to drive our strategy. He will be remembered by those who had the pleasure of knowing him as a warm and incredibly bright individual of high integrity. For all who knew Sunil, we will honor his legacy as we advance our work.” With more than 25 years of senior management and R&D experience in the biotechnology industry, Mr. Patel most recently worked as an independent consultant to biotechnology companies advising on strategy and corporate development initiatives. Previously, he served in executive roles at OncoMed Pharmaceuticals, Inc., including Executive Vice President and Chief Financial Officer. He held senior management positions in corporate development, marketing and strategy with BiPar Sciences, Inc., Allos Therapeutics, Inc., Connetics, Abgenix, Inc. and Gilead Sciences Inc. Early in his career Mr. Patel worked at McKinsey & Company serving biotechnology and pharmaceutical clients, and held scientific research positions at ZymoGenetics, Inc. and ProCyte Corporation. He received an undergraduate degree in chemistry from the University of California, Berkeley and a master’s degree in molecular bioengineering/biotechnology from the University of Washington. About OmniAb® OmniAb’s discovery platform provides pharmaceutical industry partners access to diverse antibody repertoires and high-throughput screening technologies to enable discovery of next-generation therapeutics. At the heart of the OmniAb platform is the Biological Intelligence™ (BI) of our proprietary transgenic animals, including OmniRat®, OmniChicken® and OmniMouse® that have been genetically modified to generate antibodies with human sequences to facilitate development of human therapeutic candidates. OmniFlic® (transgenic rat) and OmniClic® (transgenic chicken) address industry needs for bispecific antibody applications though a common light chain approach, and OmniTaur™ features unique structural attributes of cow antibodies for complex targets. We believe the OmniAb animals comprise the most diverse host systems available in the industry and they are optimally leveraged through computational antigen design and immunization methods, paired with high-throughput single B cell phenotypic screening and mining of next-generation sequencing datasets with custom algorithms to identify fully human antibodies with superior performance and developability characteristics. These proprietary technologies are joined with and leverage OmniDeep, which is a suite of in silico tools for therapeutic discovery and optimization that are woven throughout OmniAb’s various technologies and capabilities. Additionally, an established core competency focused on ion channels and transporters further differentiates OmniAb’s technology and creates opportunities in many emerging target classes. OmniAb antibodies have been leveraged across modalities, including bispecific antibodies, antibody-drug conjugates and others. The OmniAb suite of technologies span from BI-powered repertoire generation to cutting-edge antibody discovery and optimization offering a highly efficient and customizable end-to-end solution for the growing discovery needs of the global pharmaceutical industry. For more information, please visit . View source version on businesswire.com: Contacts OmniAb, Inc. Neha Singh, Ph.D. investors@OmniAb.com Twitter (X) @OmniAbTech (510) 768-7760 Source: OmniAb, Inc. View this news release online at:

CAMBRIDGE, Mass.--( BUSINESS WIRE )--PROMETRIKA, LLC has announced that it has expanded its strategic regulatory consulting services under the leadership of Aileen Ryan, MS, Senior Regulatory Advisor, who has been providing regulatory consulting services to PROMETRIKA’s client companies on a part-time basis for the past 2 years has now joined the company on a full-time basis. Ms. Ryan brings to this position over 40 years of diverse experience in pharmaceutical regulatory affairs, including regulatory strategy, submission preparation (IND/NDA/BLA/MAA), and health authority interactions. Her experience spans submissions in the US, Canada, EU, and Japan. Other leadership roles have included supervision of clinical quality assurance, medical writing, and safety functions. At PROMETRIKA, Ms. Ryan will spearhead regulatory affairs activities and will be available to provide its sponsors with strategic consulting and regulatory support from the pre-IND phase through marketing application preparation and approval, and continuing with life-cycle management. Ms. Ryan will also be providing the regulatory perspective to PROMETRIKA’s Clinical Operations, Pharmacovigilance, Biostatistics, and Medical Writing functions, which will further enhance PROMETRIKA’s delivery of best-in-class services. “Aileen’s experience and approach are a natural fit for our company,” commented Miganush Stepanians, President & CEO. “As a leader in regulatory affairs, she has always excelled at translating business and scientific objectives by providing regulatory support and guidance to clinical plans, ensuring high levels of quality and efficiency. This approach is one of the many reasons I am excited to have her join our leadership team.” Prior to joining PROMETRIKA, Ms. Ryan’s leadership roles have included Head of Regulatory Affairs and Compliance at the Ludwig Institute for Cancer Research, Vice President of Regulatory Affairs at Allos Therapeutics, Ophtherion, and Vion Pharmaceuticals, and Head of Global Regulatory Strategy for Oncology at Bayer Pharmaceuticals. Her work has covered drugs, biologics, and devices across a wide range of therapeutic areas. Recent areas of focus have centered on oncology, particularly early phase studies of immunotherapy treatments. “I am eager to bring my years of experience to PROMETRIKA and its clients,” said Ms. Ryan “I am equally as enthusiastic to be part of an organization that sees the value in a collaborative team approach to clinical trials, and look forward to working with the entire team.” Ms. Ryan received her Bachelor of Science degree in Biochemistry from the University Massachusetts at Amherst and a Master’s of Science in Basic Medical Sciences from New York Medical College. About PROMETRIKA, LLC - www.prometrika.com Founded in 2003 and based in Cambridge, Massachusetts, PROMETRIKA is a unique Clinical Research Organization (CRO), utilizing a collaborative approach to clinical development and execution with a close‑knit, highly‑experienced senior leadership team involved in all phases of trials. PROMETRIKA’s services include complete clinical operations and clinical trial management, data management, pharmacovigilance, biostatistics and programming, medical writing, and regulatory submissions.