Shenzhen Taitai Pharmaceutical Co., Ltd.

Main research purpose: To study the pharmacokinetic characteristics of formoterol after a single inhalation of formoterol fumarate inhalation aerosol with high and low specifications and Symbicort® in healthy subjects; to further confirm the rationality of the development specifications of formoterol fumarate inhalation aerosol and the in vivo linear relationship between high and low specifications Secondary research purpose: To study the blocking effect of oral administration of a certain dose of activated carbon on the gastrointestinal absorption of formoterol

Main research objectives: To determine the pharmacokinetic parameters of the test preparation and the reference preparation under fasting conditions in healthy subjects, to examine the rationality of blood sampling, dosing, etc., and to verify the blood drug concentration analysis method. Secondary research objectives: To examine the safety of the test preparation and the reference preparation in healthy subjects.

To evaluate the efficacy and safety of formoterol fumarate inhalation solution in the treatment of chronic obstructive pulmonary disease in adults