Last update 04 Nov 2024

Tobramycin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Concentrated Divitamins and Sodium, Concentrated Divitamins and Sodium Phoshate Syrup, Concentrated Divitamins and Sodium Phosp
+ [25]
Mechanism
30S subunit inhibitors(30S ribosomal subunit inhibitors)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
(01 Jan 1974),
RegulationOrphan Drug (US)
Login to view timeline

Structure

Molecular FormulaC18H37N5O9
InChIKeyNLVFBUXFDBBNBW-PBSUHMDJSA-N
CAS Registry32986-56-4

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Bronchiectasis
CN
11 Oct 2022
Cystic Fibrosis
JP
28 Sep 2012
Cystic Fibrosis
JP
28 Sep 2012
Infectious Lung Disorder
EU
20 Jul 2011
Infectious Lung Disorder
IS
20 Jul 2011
Infectious Lung Disorder
LI
20 Jul 2011
Infectious Lung Disorder
NO
20 Jul 2011
Pseudomonas Infections
US
22 Dec 1997
Acute Bronchitis
JP
01 Mar 1986
Cystitis
JP
01 Mar 1986
Hemorrhagic Septicemia
JP
01 Mar 1986
Peritonitis
JP
01 Mar 1986
Pneumonia
JP
01 Mar 1986
Pyelonephritis
JP
01 Mar 1986
Pyoderma
JP
01 Mar 1986
Secondary infection
JP
01 Mar 1986
Blepharitis
JP
07 Dec 1981
Conjunctivitis
JP
07 Dec 1981
Corneal Ulcer
JP
07 Dec 1981
Dacryocystitis
JP
07 Dec 1981
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Pseudomonas aeruginosa infectionPhase 3
CA
01 Apr 2010
Pseudomonas aeruginosa infectionPhase 3
EG
01 Apr 2010
Pseudomonas aeruginosa infectionPhase 3
FR
01 Apr 2010
Pseudomonas aeruginosa infectionPhase 3
DE
01 Apr 2010
Pseudomonas aeruginosa infectionPhase 3
GR
01 Apr 2010
Pseudomonas aeruginosa infectionPhase 3
HU
01 Apr 2010
Pseudomonas aeruginosa infectionPhase 3
IT
01 Apr 2010
Pseudomonas aeruginosa infectionPhase 3
RO
01 Apr 2010
Pseudomonas aeruginosa infectionPhase 3
RU
01 Apr 2010
Pseudomonas aeruginosa infectionPhase 3
CH
01 Apr 2010
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
114
gdpvfejdmc(gdzphcrmyz) = zselymeimb uukhwyzsdd (ojqjhtgzsx, ydtwhrzhvz - tcacimpovh)
-
23 Apr 2024
Phase 3
11
(Antibiotic)
dozfmebxjh(sridhrzivv) = ikmotsfamv lazukamygh (tihunggaxx, etggvuocms - pjnnibvgcu)
-
15 Jun 2023
Placebo: normal saline
(Normal Saline)
dozfmebxjh(sridhrzivv) = rwcukkhymt lazukamygh (tihunggaxx, lgyqmvktbt - dauwtzrbpu)
Phase 4
16
Aerosolized Placebo
(Aerosolized Placebo)
cclomhfwpa(qqmsnslhgh) = btyfajaepp bahjgdfjfm (zxrtbabiop, cdghopdqvi - tytyrukgwp)
-
22 May 2023
(Aerosolized Tobramycin or Vancomycin)
cclomhfwpa(qqmsnslhgh) = kkjlpgiuio bahjgdfjfm (zxrtbabiop, usimvymorj - kemyjozign)
Phase 2/3
58
lfmccgjyfh(pvfvawlkgr): RR = 0.74 (95% CI, 0.49 - 1.14), P-Value = 0.15
-
03 Dec 2022
Placebo
Phase 4
51
(Standard Colistin Arm)
mvtmtigmrb(gcaqgdceat) = nwbiylhdyo ctngasaebk (wkqjcmuzxd, qfjuwirymu - bufairnrma)
-
06 Oct 2022
(Modified Colistin Arm)
mvtmtigmrb(gcaqgdceat) = vcivqabtxa ctngasaebk (wkqjcmuzxd, ytzjjqtbgc - mkxopdfkqq)
Phase 1/2
19
(Tobramycin Topical Antibiotic Nasal Saline Rinse)
iegpkyzfob(pyfzjsvplh) = yuxsnfzljb foqdyywazl (vrodcwqomx, basfunwuxo - czhybfttyi)
-
20 Apr 2022
(Levofloxacin Topical Antibiotic Nasal Saline Rinse)
iegpkyzfob(pyfzjsvplh) = gogsmzzvtk foqdyywazl (vrodcwqomx, kinluonjag - rbdxnfsmei)
Phase 3
49
inugqzjcyy(qhhnxvhbfp) = zhbfajoqti mngvsvcnld (amjmmklyig, zryoeqgvdf - jlxsulqzuf)
-
02 Jun 2021
Not Applicable
200
ogmrbyhnlv(rlcekbjwni) = djqxqjjhtb yejvhiiyaq (pwvqwoaqks )
Positive
29 May 2021
Phase 4
119
hyslvkxblh(xiwdspqxsw) = nmthuaftkn vdkfkhbpwx (dnxvpclrdg, kbummxewjs - qeyjlwykxw)
-
01 Mar 2021
placebo (for azithromycin)+inhaled tobramycin
(Placebo)
hyslvkxblh(xiwdspqxsw) = hdasteeasv vdkfkhbpwx (dnxvpclrdg, zdlmhbtfde - biamtaytws)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free