Shanghai Xinshengyuan Biological Medicine Co. Ltd.

To evaluate the clinical safety and efficacy of freeze-dried recombinant human keratinocyte growth factor-2 in the treatment of superficial second-degree burns on the skin, explore the effective therapeutic dose, and provide scientific experimental basis for phase III clinical trials.

Evaluation of the safety, tolerability and pharmacokinetics of freeze-dried recombinant human keratinocyte growth factor-2 for topical treatment of skin partial second-degree burns (two-center, open, multiple doses, wound absorption)

To observe the safety and tolerability of topical application of rhKGF-2 to the skin of healthy Chinese subjects;