Last update 01 Nov 2024

ENO1

Basic Info

Synonyms
2-phospho-D-glycerate hydro-lyase, Alpha-enolase, C-myc promoter-binding protein
+ [12]
Introduction
Binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor. Glycolytic enzyme the catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate (PubMed:29775581, PubMed:1369209). In addition to glycolysis, involved in various processes such as growth control, hypoxia tolerance and allergic responses (PubMed:2005901, PubMed:10802057, PubMed:12666133, PubMed:29775581). May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons (PubMed:12666133). Stimulates immunoglobulin production (PubMed:1369209).

Analysis

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