A Randomized, Placebo-Controlled, Double-Blind, Crossover Comparative Study of the Effect of Acotiamide on Gastrointestinal Symptoms in Patients with Myasthenia Gravis - ACTMG
Main purpose: Taking acotiamide hydrochloride tablets (trade name: Acofide®, specification: 100mg), which is licensed by Alyas Shinsui Industrial Co., Ltd./Asui Rakusu Co., Ltd., as the reference preparation, Nanjing Haina Pharmaceutical Technology Co., Ltd. The acotiamide hydrochloride tablets (0.1g) developed by the company are the test preparations and were evaluated through a single-center, randomized, open-label, single-dose, two-preparation, two-sequence, four-cycle, fully repeated crossover design clinical trial. Bioequivalence of two formulations in fasting and postprandial states in Chinese healthy subjects.
Secondary purpose: To observe the safety of the test preparation and reference preparation in Chinese healthy subjects.
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