Last update 08 May 2025

AMPA receptor x VGSCs x CAs x GABAA receptor

Basic Info

Related Targets
AMPA receptorVGSCsCAs[+1]

Related

1
Drugs associated with AMPA receptor x VGSCs x CAs x GABAA receptor
Topiramate
Target
AMPA receptor x CAs x GABAA receptor x VGSCs
Mechanism
AMPA receptor antagonists [+3]
Active Org.
Janssen Pharmaceuticals, Inc.Janssen Pharmaceuticals, Inc. [+8]
Originator Org.
Janssen Global Services LLCJanssen Global Services LLC
Active Indication
Epilepsy [+6]
Inactive Indication
Affective Disorders, Psychotic [+26]
Drug Highest PhaseApproved
First Approval Ctry. / Loc.
United States
First Approval Date24 Dec 1996
325
Clinical Trials associated with AMPA receptor x VGSCs x CAs x GABAA receptor
NCT05209984
/ Not yet recruitingPhase 3
A Phase 3, Randomized, Double-blind, Double-dummy, Parallel-group, Active Drug and Placebo-controlled, Safety, Efficacy and Superiority of Sibutramine IR/topiramate XR in Overweight Adults with Comorbidities/obesity
NCT04613024
/ WithdrawnEarly Phase 1IIT
Beneficial Side Effects of Topiramate in Obese Patients Undergoing Total Joint Arthroplasty, a Study of Opiate Consumption and Weight Reduction
100 Clinical Results associated with AMPA receptor x VGSCs x CAs x GABAA receptor
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100 Translational Medicine associated with AMPA receptor x VGSCs x CAs x GABAA receptor
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0 Patents (Medical) associated with AMPA receptor x VGSCs x CAs x GABAA receptor
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