Last update 21 Mar 2024


Sodium/hydrogen exchanger 3

Basic Info

钠氢交换器3, Na(+)/H(+) exchanger 3, NHE-3
+ [8]
Plasma membrane Na(+)/H(+) antiporter (PubMed:26358773, PubMed:35613257, PubMed:18829453). Exchanges intracellular H(+) ions for extracellular Na(+) in 1:1 stoichiometry, playing a key role in salt and fluid absorption and pH homeostasis (By similarity). Major apical Na(+)/H(+) exchanger in kidney and intestine playing an important role in renal and intestine Na(+) absorption and blood pressure regulation (PubMed:26358773, PubMed:24622516).


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