Last update 21 Mar 2024

D2 receptor x α1B-AR x hERG x D1 receptor x α1A-AR x 5-HT2A receptor

Dopamine D2 receptor x Alpha-1b adrenergic receptor x Voltage-gated potassium channel subunit Kv11.1 x Dopamine D1 receptor x Alpha-1a adrenergic receptor x Serotonin 2a (5-HT2a) receptor

Basic Info

Related Targets
D2 receptorα1B-ARhERG[+3]

Related

1
Drugs associated with D2 receptor x α1B-AR x hERG x D1 receptor x α1A-AR x 5-HT2A receptor
Thioridazine
Target
5-HT2A receptor x D1 receptor x D2 receptor x hERG x α1A-AR x α1B-AR
Mechanism
5-HT2A receptor antagonists [+5]
Active Org.
Beijing Suopingda Pharmaceutical Research Co Ltd
Originator Org.
Novartis Pharma AG
Active Indication
Hepatocellular Carcinoma
Inactive Indication
Generalized anxiety disorder [+1]
Drug Highest PhasePhase 3
First Approval Ctry. / Loc.
US
First Approval Date18 Oct 1978
7
Clinical Trials associated with D2 receptor x α1B-AR x hERG x D1 receptor x α1A-AR x 5-HT2A receptor
CTR20221306 / RecruitingPhase 3
TP21注射液用于TACE治疗肝细胞癌的有效性和安全性的随机、开放、平行对照、多中心Ⅲ期临床试验
[Translation] A randomized, open, parallel-controlled, multicenter phase III clinical trial of the efficacy and safety of TP21 injection for TACE in the treatment of hepatocellular carcinoma
CTR20181994 / RecruitingPhase 2
TP21注射液用于TACE治疗肝细胞癌的有效性和安全性的随机、开放、平行对照、多中心探索性临床试验
[Translation] A randomized, open-label, parallel-controlled, multicenter exploratory clinical trial of the efficacy and safety of TP21 injection for TACE in the treatment of hepatocellular carcinoma
100 Clinical Results associated with D2 receptor x α1B-AR x hERG x D1 receptor x α1A-AR x 5-HT2A receptor
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100 Translational Medicine associated with D2 receptor x α1B-AR x hERG x D1 receptor x α1A-AR x 5-HT2A receptor
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0 Patents (Medical) associated with D2 receptor x α1B-AR x hERG x D1 receptor x α1A-AR x 5-HT2A receptor
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