Last update 01 Nov 2024

PHGDH

Basic Info

Synonyms
2-oxoglutarate reductase, 3-PGDH, D-3-phosphoglycerate dehydrogenase
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Introduction
Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate.

Analysis

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