Synonyms 1,4-alpha-D-glucan glucanohydrolase 1, Alpha-amylase 1A, AMY1 + [6] |
Introduction Calcium-binding enzyme that initiates starch digestion in the oral cavity (PubMed:12527308). Catalyzes the hydrolysis of internal (1->4)-alpha-D-glucosidic bonds, yielding a mixture of maltose, isomaltose, small amounts of glucose as well as small linear and branched oligosaccharides called dextrins (PubMed:12527308). |
Mechanism AMY1A inhibitors [+2] |
Active Org.- |
Active Indication- |
Inactive Indication |
Drug Highest PhaseDiscontinued |
First Approval Ctry. / Loc.- |
First Approval Date20 Jan 1800 |
Target |
Mechanism AMY1A inhibitors |
Active Org.- |
Originator Org. |
Active Indication- |
Inactive Indication |
Drug Highest PhaseDiscontinued |
First Approval Ctry. / Loc.- |
First Approval Date20 Jan 1800 |
Start Date19 Sep 2018 |
Sponsor / Collaborator |
Start Date30 Mar 2015 |
Sponsor / Collaborator |
Start Date01 Sep 2012 |
Sponsor / Collaborator |