Last update 21 Mar 2024

CD28

T-cell-specific surface glycoprotein CD28

Basic Info

Synonyms
CD28抗原, CD28, CD28 antigen (Tp44)
+ [4]
Introduction
Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation (PubMed:8617933). Isoform 3 enhances CD40L-mediated activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells (PubMed:15067037).

Analysis

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