Last update 08 May 2025

NS5B polymerase x RNGTT x IMPDH x RNAP

Basic Info

Related Targets
NS5B polymeraseRNGTTIMPDH[+1]

Related

2
Drugs associated with NS5B polymerase x RNGTT x IMPDH x RNAP
Sofosbuvir/Ribavirin/Epigallocatechin Gallate
Target
IMPDH x NS5B polymerase x RNAP x RNGTT
Mechanism
IMPDH inhibitors [+3]
Active Org.
Virothera Pharmaceuticals
Originator Org.
Virothera Pharmaceuticals
Active Indication
Hepatitis C
Inactive Indication-
Drug Highest PhasePhase 3
First Approval Ctry. / Loc.-
First Approval Date20 Jan 1800
Epigallocatechin Gallate/Sofosbuvir/Daclatasvir/Ribavirin
Target
IMPDH x NS5A x NS5B polymerase x RNAP x RNGTT
Mechanism
IMPDH inhibitors [+4]
Active Org.-
Originator Org.-
Active Indication-
Inactive Indication
Hepatitis C
Drug Highest PhasePending
First Approval Ctry. / Loc.-
First Approval Date20 Jan 1800
5
Clinical Trials associated with NS5B polymerase x RNGTT x IMPDH x RNAP
NCT03186313
/ CompletedPhase 3IIT
A Phase 3 Randomized, Open-Label, Study to Evaluate the Safety and Efficacy of the Combined Single Dose of Dactavira Plus (EPGCG, Sofosbuvir , Daclatasvir & Ribavirin) Versus Sofosbuvir + Daclatasvir + Ribavirin (Part A) and a Single Dose of Dactavira (EPGCG, Sofosbuvir & Daclatasvir) Versus Sofosbuvir + Daclatasvir (Part B) in Egyptian Adults With Chronic Genotype 4 HCV Infection
100 Clinical Results associated with NS5B polymerase x RNGTT x IMPDH x RNAP
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100 Translational Medicine associated with NS5B polymerase x RNGTT x IMPDH x RNAP
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0 Patents (Medical) associated with NS5B polymerase x RNGTT x IMPDH x RNAP
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