Last update 01 Nov 2024

PORCN

Basic Info

Synonyms
dermal hypoplasia, focal, DHOF, MG61
+ [8]
Introduction
Protein-serine O-palmitoleoyltransferase that acts as a key regulator of the Wnt signaling pathway by mediating the attachment of palmitoleate, a 16-carbon monounsaturated fatty acid (C16:1(9Z)), to Wnt proteins. Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors.

Analysis

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