Last update 21 Mar 2024

PRDX3

peroxiredoxin 3

Basic Info

Synonyms
Antioxidant protein 1, AOP-1, AOP1
+ [11]
Introduction
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides (PubMed:7733872, PubMed:17707404, PubMed:29438714, PubMed:33889951). Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol (PubMed:12492477). Required for the maintenance of physical strength (By similarity).

Analysis

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