German pharmaceutical firm
Boehringer Ingelheim has outlined a bold strategy to introduce 25 innovative treatments by the year 2030. This initiative is part of their 2023 financial report, where they have also outlined plans to initiate 10 new clinical trials in the next 12 to 18 months.
The company's late-stage research is gaining momentum, especially in the fields of oncology, mental health, cardiovascular, renal, and metabolic diseases. In 2023, the FDA recognized their efforts by granting them five fast-track designations and one breakthrough therapy designation.
Boehringer has highlighted several promising drug candidates. One of these is
Brigimadlin, an
MDM2-
p53 agonist, which has advanced to a pivotal trial for treating
dedifferentiated liposarcoma. Another is
zongertinib, an investigational
HER2 tyrosine kinase inhibitor, whose development has been expedited following positive initial findings.
In 2024, Boehringer's candidate
survodutide for treating
metabolic dysfunction-associated steatohepatitis showed significant promise, with 83% of patients experiencing an improvement in
liver disease without
fibrosis progression. This candidate is now entering Phase III trials for
obesity.
Hubertus von Baumbach, the chairman of Boehringer Ingelheim's board of managing directors, expressed his enthusiasm for the company's balanced and robust pipeline. He emphasized the company's commitment to accelerating the development of new treatments and making them accessible to patients as quickly and efficiently as possible. The aim is to improve healthcare systems and make them more equitable.
Despite the optimistic outlook, the company has faced challenges with the sales of its
Humira biosimilar,
Cyltezo, in the U.S. market. Slow sales have led to staff reductions, as
AbbVie has managed to stave off competition from biosimilars for now.
However, Boehringer reported a 9.7% increase in net sales for 2023, driven by the sales of
Jardiance, a treatment for
diabetes and
heart failure, and
Ofev, a treatment for
pulmonary fibrosis. The company's 2023 group net sales reached €25.6 billion, with a 10.3% growth in the human pharmaceutical sector. Jardiance sales increased by 31% to €7.4 billion, while Ofev sales rose by 12.8% to €3.5 billion.
Boehringer Ingelheim's ambitious pipeline and financial growth underscore the company's dedication to advancing healthcare and addressing unmet medical needs.
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