Biological Glossary | What is Fusion Protein?
A fusion protein is a protein composed of at least two domains that are encoded by separate genes fused together so that they are transcribed and translated as a single unit, producing a single polypeptide. These proteins can occur naturally due to chromosomal rearrangement or be created artificially using recombinant DNA techniques. Recombinant fusion proteins are used in biological research and therapeutics. Fusion proteins can be found in cancer cells where they can function as oncoproteins. Fusion proteins, also known as fusion tag proteins or chimeric proteins, can be created using recombinant protein tags.
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