Xenoview, with the generic name xenon Xe 129 hyperpolarized, is a diagnostic radiopharmaceutical used as a contrast agent for magnetic resonance imaging (MRI) scans. Xenoview received FDA approval on December 23, 2022. It plays a crucial role in providing clearer images of certain areas of the body, particularly the lungs, without the need for radiation exposure.
Xenoview is an inhaled contrast agent used to improve the clarity of MRI scans, specifically for diagnosing issues in the lungs. MRI scans use magnets and computers to create detailed images of the body. Unlike x-rays, MRI scans do not involve radiation, making them safer for repeated use. Xenon Xe 129 is hyperpolarized, meaning it enhances the MRI images by providing a more detailed contrast.
Xenoview is administered in a hospital setting by a doctor or trained health professional. Patients inhale the contrast agent through a mouthpiece placed over their mouth just before undergoing an MRI scan. The typical dosage and administration instructions are provided by the healthcare professional based on the specific needs of the patient.
Before using Xenoview, patients should discuss any allergies with their doctor, including reactions to medicines, foods, dyes, preservatives, or animals. The safety and efficacy of Xenoview in children under 6 years old have not been established, and appropriate studies have not shown any geriatric-specific problems for elderly patients. For breastfeeding women, there are no adequate studies to determine infant risk, so the potential benefits and risks should be carefully weighed.
Patients should inform their healthcare provider about any other medications they are taking, including prescription, over-the-counter, vitamins, and herbal supplements. Xenoview is unlikely to interact with other medications due to its administration method directly into the lungs, but patients should still discuss any potential interactions with their doctor.
While Xenoview is generally safe, some side effects may occur. Common side effects include headache and pain in the mouth and throat. More serious side effects, although less common, may include transient hypoxia (low oxygen levels in the body), confusion, dizziness, fast heartbeat, trouble breathing, and weakness. Patients should seek immediate medical attention if they experience any severe side effects.
Xenoview, approved by the FDA on December 23, 2022, is a significant advancement in diagnostic imaging for lung conditions. As a hyperpolarized MRI contrast agent, it provides clearer and more detailed images, aiding in accurate diagnoses without the risks associated with radiation. Patients considering this diagnostic tool should consult with their healthcare provider to ensure it is the right choice for their specific medical needs.
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