Last update 21 Mar 2024

Chronic Kidney Disease-Mineral and Bone Disorder

Basic Info

Synonyms
CKD-MBD, CKD-MBD - chronic kidney disease mineral and bone disorder, CKDMBD
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Introduction
Decalcification of bone or abnormal bone development due to chronic KIDNEY DISEASES, in which 1,25-DIHYDROXYVITAMIN D3 synthesis by the kidneys is impaired, leading to reduced negative feedback on PARATHYROID HORMONE. The resulting SECONDARY HYPERPARATHYROIDISM eventually leads to bone disorders.

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