Chancroid

FRIDAY, Jan. 26, 2024 -- Childhood bacterial meningitis significantly increases the risk for having at least one of seven long-term disabilities, according to a study published online Jan. 19 in JAMA Network Open . Salini Mohanty, Dr.P.H., from Merck & Co. Inc. in Rahway, New Jersey, and colleagues assessed the long-term risk for disabilities among individuals diagnosed with bacterial meningitis in childhood. The analysis included 36,230 Swedish individuals diagnosed with bacterial meningitis (younger than 18 years) and matched (1:9) general population controls with up to 35 years of follow-up (1987 through 2021). The researchers found that individuals diagnosed with bacterial meningitis had a higher cumulative incidence of all seven examined disabilities (cognitive disabilities, seizures, hearing loss, motor function disorders, visual disturbances, behavioral and emotional disorders, and intracranial structural injuries), with 29.0 percent having at least one disability. The highest relative risk for cases versus controls was seen for intracranial structural injuries (hazard ratio, 26.04), hearing loss (hazard ratio, 7.90), and motor function disorders (hazard ratio, 4.65). Risks for cognitive disabilities, seizures, hearing loss, and motor function disorders were significantly higher for Streptococcus pneumoniae infection versus Haemophilus influenzae infection or Neisseria meningitidis infection. Risk for cognitive disabilities, seizures, behavioral and emotional disorders, and intracranial structural injuries were significantly higher for children diagnosed with bacterial meningitis younger than the median age (1.5 years at diagnosis). "The relative risk of disabilities tended to be highest during the first years after a diagnosis of bacterial meningitis but remained higher during the period starting over five years after diagnosis, suggesting that bacterial meningitis has both acute and long-term consequences," the authors write. Several authors disclosed ties to the pharmaceutical industry. Abstract/Full Text Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions. Posted January 2024 More news resources FDA Medwatch Drug Alerts Daily MedNews News for Health Professionals New Drug Approvals New Drug Applications Drug Shortages Clinical Trial Results Generic Drug Approvals Subscribe to our newsletter Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.

GRAND RAPIDS, Mich., Aug. 10, 2022 /PRNewswire/ -- NxGen MDx begins offering testing in Michigan and Chicago, IL for monkeypox, shingles, and lesion-forming STIs including chancroid, syphilis, and herpes. On July 23, the World Health Organization (WHO) declared monkeypox a global health emergency, and last week the U.S. Department of Health and Human Services declared that the spread of monkeypox is a public health emergency. 1 2 Already there are more than 7,500 cases in the US alone with cases doubling in Michigan and Illinois. 3 However, the true number of infections is likely much higher due to a lack of confirmatory testing and missing links in the chain of infection. With numbers still low in certain areas, now is the time to focus on preventing further mass outbreaks. While initially, monkeypox has been prevalent in men who have sex with men, it is not an STI, and anyone can be infected with monkeypox. 4 The virus has since begun to hit other vulnerable populations such as travelers, pregnant women, and children. While monkeypox primarily spreads from prolonged skin-to-skin contact such as sex, hugging, or breastfeeding, it can also be contracted from contaminated towels, sheets, and other objects, putting travelers as well as housekeeping staff at a higher risk of exposure. 5 As Michigan ranks 19th and Illinois ranks 5th in the country for Monkeypox cases with 85% of Illinois' cases residing in Chicago, residents need to have easy access to testing to help keep the virus from spreading. 3 6 By knowing what symptoms to look for, such as small rashes and lesions, people can get tested at the first sign of an infection and quickly learn if they have monkeypox, an STI, or another virus that may have similar symptoms. Because there are shared symptoms between monkeypox, certain STIs, and other viral infections, NxGen MDx has developed a panel that not only tests for monkeypox but also shingles and lesion-forming STIs. "Monkeypox signs and symptoms overlap with those of other infections. By including varicella-zoster and other pathogens with a similar presentation, our panel is designed to help clinicians identify pathogens in a lesion swab sample and determine the cause of a patient's symptoms efficiently," said NxGen MDx's Scientific Director, Jacqueline Peacock, Ph.D. Testing is the number one way to help slow the spread of the virus as it speeds up the diagnostic process, gets patients treatment faster, and helps track where the virus has spread. By offering patients this panel, NxGen MDx is ensuring that everyone has access to reliable testing that will offer more answers than testing for monkeypox alone and will help keep patients and their communities safe here in Michigan and Chicago. About NxGen MDx NxGen MDx, LLC is a leading healthcare company delivering comprehensive genetic testing. NxGen MDx's history of next-generation sequencing combined with advanced technology allows us to provide accessible, high-quality testing options to families as they plan for the future. References: 1. Second meeting of the International Health Regulations (2005) (IHR) Emergency Committee regarding the multi-country outbreak of monkeypox [Internet]. [cited 2022 Jul 27]. Available from: (2005)-(ihr)-emergency-committee-regarding-the-multi-country-outbreak-of-monkeypox 2. Affairs (ASPA) AS for P. Biden-Harris Administration Bolsters Monkeypox Response; HHS Secretary Becerra Declares Public Health Emergency [Internet]. HHS.gov. 2022 [cited 2022 Aug 8]. Available from: 3. CDC. Monkeypox in the U.S. [Internet]. Centers for Disease Control and Prevention. 2022 [cited 2022 Aug 08]. Available from: 4. Monkeypox: public health advice for gay, bisexual and other men who have sex with men [Internet]. [cited 2022 Jul 8]. who.int/news/item/25-05-2022-monkeypox--public-health-advice-for-gay--bisexual-and-other-men-who-have-sex-with-men 5. Ramey E, Paxson J. Mid-Michigan doctors talk Monkeypox spreading, symptoms [Internet]. [cited 2022 Aug 8]. Available from: 6. MPV Data Dashboard [Internet]. [cited 2022 Aug 9]. Available from: SOURCE NxGen MDx