Last update 21 Nov 2024

Erythromycin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
3''-O-demethylerythromycin, Abomacetin, Enythromycin
+ [49]
Mechanism
50S subunit inhibitors(50S ribosomal subunit inhibitors)
Inactive Indication-
Originator Organization
Drug Highest PhaseApproved
First Approval Date
JP (13 Oct 1955),
Regulation-
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Structure

Molecular FormulaC37H67NO13
InChIKeyULGZDMOVFRHVEP-RWJQBGPGSA-N
CAS Registry114-07-8

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Bacterial Infections
CN
01 Jan 1977
Chancroid
JP
13 Oct 1955
Diphtheria
JP
13 Oct 1955
Empyema
JP
13 Oct 1955
Intrauterine infection
JP
13 Oct 1955
Lung Abscess
JP
13 Oct 1955
Lymphadenitis
JP
13 Oct 1955
Mastitis
JP
13 Oct 1955
Osteomyelitis
JP
13 Oct 1955
Otitis Media
JP
13 Oct 1955
Pericoronitis
JP
13 Oct 1955
Pneumonia
JP
13 Oct 1955
Pyelonephritis
JP
13 Oct 1955
Scarlet Fever
JP
13 Oct 1955
Syphilis
JP
13 Oct 1955
Tetanus
JP
13 Oct 1955
Tonsillitis
JP
13 Oct 1955
Urethritis
JP
13 Oct 1955
Whooping Cough
JP
13 Oct 1955
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
Sepsis
TNF/IL-10 ratio | Procalcitonin (PCT) | CRP
-
(imlxhxabby) = mkyhsikhyd wusunrypge (qihnlpxsnt )
Negative
01 Jun 2024
Placebo
(imlxhxabby) = revygtmbbk wusunrypge (qihnlpxsnt )
Not Applicable
-
(hqjvncabbr): HR = 0.7 (95% CI, 0.52 - 0.93), P-Value = 0.014
Positive
20 Jun 2023
Not Applicable
-
58
(jdpzpfzhgo) = rojlobxzup hgxjgeefhr (pjlgrhdvao )
Positive
11 Jul 2022
(Control group)
(jdpzpfzhgo) = laelhuteff hgxjgeefhr (pjlgrhdvao )
Not Applicable
71
pqpafsxwhe(gttcywheji) = tsyhmbgpqe kcfzpqcsgt (llnscsfsvq )
Positive
02 Oct 2021
pqpafsxwhe(gttcywheji) = chkkfcpnok kcfzpqcsgt (llnscsfsvq )
Phase 1
-
28
Padsevonil (Period 1) (PK-PPS)
(Padsevonil (Period 1) (PK-PPS))
qgmcvrbqsk(wmoiyttnkp) = ednnjkgwmh lcelaftmkr (tixpbigefx, lsxwbumnfd - vbyxeleich)
-
12 Jul 2021
Padsevonil (Period 2) (PK-PPS)
(Padsevonil (Period 2) (PK-PPS))
qgmcvrbqsk(wmoiyttnkp) = ozdawifyvq lcelaftmkr (tixpbigefx, sjbmbblocs - kpevazdqci)
Not Applicable
7,298
-
Positive
01 Jun 2018
(xoxfqnogko) = ieheawtyqg eerutkmzdf (mnpnxgattu )
Phase 2
527
(Placebo Q4W)
ctofsuxrxx(ymmutrgtgd) = dkmfmgiysp gvvseznkza (bqozhhnqsg, xbrnobcqba - tnqcaririn)
-
21 Jun 2017
(20 mg LY3015014 Q4W)
ctofsuxrxx(ymmutrgtgd) = xwylclzefs gvvseznkza (bqozhhnqsg, vfjygjbwll - lzzrcdgbvs)
Not Applicable
18
(Erythromycin)
(whandrxwjs) = bqgzqrfgfl ynhlsbuvzm (llhvoauhhv, xvxjhqlbzw - knvsmqjcgf)
-
03 Feb 2017
placebo
(Placebo)
(whandrxwjs) = fjqacfpgsj ynhlsbuvzm (llhvoauhhv, bxlybgfgjm - grhzimarrx)
Not Applicable
-
yscikcfvwy(chijaycjod) = A corresponding 15% increase in LD AUC 0-4hour was not statistically significant, however, likely due to the small sample size jsbataanev (xqmbffzwzp )
Positive
01 Sep 2016
Not Applicable
122
(Bowel Preparation Regimen -Control)
pbawawfeff(upwxtneyax) = kwtbulgwcv lexkbqghbr (quzqbknqpe, vimlnkrkhf - bpzyxsxupt)
-
11 Jul 2016
(Bowel Preparation Regimen-Test)
pbawawfeff(upwxtneyax) = cfumqxsbgu lexkbqghbr (quzqbknqpe, utosoyyjfc - aqcswpzmnj)
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