Synonyms Disease, Fothergill, Epileptiform Neuralgia, Epileptiform Neuralgias + [64] |
Introduction A syndrome characterized by recurrent episodes of excruciating pain lasting several seconds or longer in the sensory distribution of the TRIGEMINAL NERVE. Pain may be initiated by stimulation of trigger points on the face, lips, or gums or by movement of facial muscles or chewing. Associated conditions include MULTIPLE SCLEROSIS, vascular anomalies, ANEURYSMS, and neoplasms. (Adams et al., Principles of Neurology, 6th ed, p187) |
Target |
Mechanism CALCRL antagonists |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. US |
First Approval Date27 Feb 2020 |
Target |
Mechanism TRPV1 agonists |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. CA |
First Approval Date15 Jul 2010 |
Target |
Mechanism SNAP25 inhibitors |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. DE |
First Approval Date24 Oct 2007 |
Start Date01 Jan 2025 |
Sponsor / Collaborator- |
Start Date31 Dec 2024 |
Sponsor / Collaborator |
Start Date16 Dec 2024 |
Sponsor / Collaborator |