Drug Type Small molecule drug |
Synonyms (Z)-Capsaicin, Civamide, Civanex + [6] |
Target |
Mechanism TRPV1 agonists(Vanilloid receptor agonists) |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date CA (15 Jul 2010), |
RegulationOrphan Drug (US) |
Molecular FormulaC18H27NO3 |
InChIKeyYKPUWZUDDOIDPM-VURMDHGXSA-N |
CAS Registry25775-90-0 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D06388 | Zucapsaicin |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Osteoarthritis | CA | - | 15 Jul 2010 |
Pain | CA | - | 15 Jul 2010 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Trigeminal Neuralgia | Preclinical | US | 01 Mar 2014 | |
Neuralgia, Postherpetic | Preclinical | US | 01 Mar 2009 | |
Neuralgia, Postherpetic | Preclinical | CA | 01 Mar 2009 | |
Dry Eye Syndromes | Discovery | US | 01 May 2014 | |
Neuralgia, Postherpetic | Discovery | US | 01 Mar 2009 | |
Neuralgia, Postherpetic | Discovery | CA | 01 Mar 2009 | |
Post-traumatic neuralgia | Discovery | CA | 01 Mar 2009 | |
Post-traumatic neuralgia | Discovery | US | 01 Mar 2009 | |
Osteoarthritis, Knee | Discovery | - | 01 Jun 2003 | |
Cluster Headache | Discovery | US | 01 Jan 2002 |
Phase 2 | 232 | osfvcqgozb(bkezenaodk) = xtfffssedt tpzbgupblo (sixcnkgfii, cfjouozobb - ffeowklerf) View more | - | 01 Dec 2023 | |||
Phase 2 | 63 | Combination pharmacotherapy - transdermal nicotine patch + nicotine gum+Bupropion Sustained Release+Nicotine replacement therapy - nicotine gum+Varenicline+Nicotine replacement therapy - transdermal nicotine patch (Tailored Intervention Group) | yipiqtnerk(poifbqvujz) = hgopvutgco ykyzrjjxuc (vbnjxbvxcc, qhcdejhlxf - yirypforsc) View more | - | 19 Jul 2017 | ||
Combination pharmacotherapy - transdermal nicotine patch + nicotine gum+Bupropion Sustained Release+Nicotine replacement therapy - nicotine gum+Varenicline+Nicotine replacement therapy - transdermal nicotine patch (Enhanced Standard of Care Group) | yipiqtnerk(poifbqvujz) = mzktjajmyk ykyzrjjxuc (vbnjxbvxcc, tpsdaxnxll - foagqhoikt) View more | ||||||
Phase 2 | 11 | (Double Blind Treatment Period Civamide Nasal Spray) | rcbultibyt(jkkgzpmput) = uvcmcxebxv jramuavsdn (ohlgccfgal, gnkeadlgcg - ilzuaezkfx) View more | - | 01 Mar 2017 | ||
Placebo (Double Blind Treatment Period Placebo Nasal Spray) | rcbultibyt(jkkgzpmput) = xboafgnwfa jramuavsdn (ohlgccfgal, turutpmlri - zonppjcxxg) View more |