Last update 01 Nov 2024

Zucapsaicin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(Z)-Capsaicin, Civamide, Civanex
+ [6]
Target
Mechanism
TRPV1 agonists(Vanilloid receptor agonists)
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
CA (15 Jul 2010),
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC18H27NO3
InChIKeyYKPUWZUDDOIDPM-VURMDHGXSA-N
CAS Registry25775-90-0

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Osteoarthritis
CA
-15 Jul 2010
Pain
CA
-15 Jul 2010
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Dry Eye SyndromesPhase 2
US
01 May 2014
Trigeminal NeuralgiaPreclinical
US
01 Mar 2014
Neuralgia, PostherpeticPreclinical
US
01 Mar 2009
Neuralgia, PostherpeticPreclinical
CA
01 Mar 2009
Neuralgia, PostherpeticDiscovery
CA
01 Mar 2009
Neuralgia, PostherpeticDiscovery
US
01 Mar 2009
Post-traumatic neuralgiaDiscovery
US
01 Mar 2009
Post-traumatic neuralgiaDiscovery
CA
01 Mar 2009
Osteoarthritis, KneeDiscovery-01 Jun 2003
Cluster HeadacheDiscovery
US
01 Jan 2002
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
232
sbsllkephi(kidbudxuzz) = sqtatdlgbp liftvaenfz (rekgvjmkfm, fhkxllgthz - ptxnuzqeqy)
-
01 Dec 2023
Phase 2
63
Combination pharmacotherapy - transdermal nicotine patch + nicotine gum+Bupropion Sustained Release+Nicotine replacement therapy - nicotine gum+Varenicline+Nicotine replacement therapy - transdermal nicotine patch
(Tailored Intervention Group)
tajxwmuvld(nfkyrjnbpk) = ztksahcywk xcgmwlesnn (psftxqzlqs, xzmctwthyp - brpfqbtvxf)
-
19 Jul 2017
Combination pharmacotherapy - transdermal nicotine patch + nicotine gum+Bupropion Sustained Release+Nicotine replacement therapy - nicotine gum+Varenicline+Nicotine replacement therapy - transdermal nicotine patch
(Enhanced Standard of Care Group)
tajxwmuvld(nfkyrjnbpk) = xteuqsfpko xcgmwlesnn (psftxqzlqs, gkrdqsoptz - fgfcyqdoil)
Phase 2
11
(Double Blind Treatment Period Civamide Nasal Spray)
nkmmabtqya(jpgdkezkqm) = scxlrsoubw nwgzrrkgbi (vtniigfaos, iwmcrsvorw - trobfewqki)
-
01 Mar 2017
Placebo
(Double Blind Treatment Period Placebo Nasal Spray)
nkmmabtqya(jpgdkezkqm) = gjhxnhdqhs nwgzrrkgbi (vtniigfaos, bxcvolkfgu - ygwbntnpxr)
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Regulation

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