Parkinson Disease, Postencephalitic

MINNEAPOLIS, Oct. 17, 2023 /PRNewswire/ -- The American Brain Foundation has launched a $10 million cross-disciplinary research initiative that transcends traditional research and philanthropy boundaries by bringing together nonprofit organizations, pharmaceutical and biotech investors, philanthropists, and researchers. The initiative will provide funding for research by top neuroscientists to investigate the role of neuroinflammation in a wide range of brain diseases, both neurologic and psychiatric, including conditions as disparate as Alzheimer's, schizophrenia, long COVID-19, and autism. The research initiative is part of the American Brain Foundation's existing Cure One, Cure Many program, which promotes innovative, cross-cutting approaches to brain disease diagnosis and treatment. Continue Reading The American Brain Foundation has launched a $10 million cross-disciplinary research initiative, bringing together nonprofit organizations, pharmaceutical and biotech investors, philanthropists, and researchers. The initiative will provide research funding for top neuroscientists to investigate the role of neuroinflammation, a contributor to almost every known neurologic and psychiatric brain disease. There are over 600 known brain diseases, and neuroinflammation plays a role in nearly all of them—yet researchers still understand very little about how this common immune response contributes to the development of neurologic disorders. This large-scale, multi-phased initiative will support research to better understand how neuroinflammation acts as an underlying mechanism across nearly all brain diseases and affects people of all ages. Unprecedented Cross-Industry Collaboration The American Brain Foundation is spearheading an unprecedented cross-industry collaboration between scientists, pharmaceutical organizations, venture and private philanthropists, and patient advocacy and nonprofit organizations like the National MS Society, the Encephalitis Society, the NFL Players Association, and the WoodNext Foundation. "The NFLPA proudly joins hands with the American Brain Foundation in advancing this extraordinary $10 million neuroinflammation initiative," said Dr. Thom Mayer, medical director for the NFL Players Association. "We are proud to be part of this historic collaboration, uniting diverse stakeholders to tackle the impact of neuroinflammation on brain health. Together, we aim to improve diagnosis, prevention, treatment, and ultimately discover cures for these conditions." The American Academy of Neurology, the American Brain Foundation's key research partner, will have a central role in the vetting of applications and selecting awardees. Chairing the initiative is Dr. Stephen Hauser, American Brain Foundation board member and director of UCSF Weill Institute for Neurosciences. "Bringing together partners from so many different fields is the fastest, most innovative way to drive forward innovative research and harness the potential of the immune system to treat, repair, and even cure some of the most devastating brain diseases and disorders," said Dr. Hauser. "The research funded by the initiative will impact diseases as widespread and different as Parkinson's, encephalitis, multiple sclerosis (MS), Alzheimer's, brain trauma, autism, and others." This large-scale, coordinated effort to support research from a wide diversity of partners and donors demonstrates both the range of concern about the impact of neuroinflammation on brain health and its significance as an emerging public health issue. "In recent years there has been an increasing interest in neuroinflammation, the role it has to play in the brain, and whether it can be a catalyst in our understanding of so many other diseases and disorders that we know so little about," said Dr. Ava Easton, chief executive of the Encephalitis Society. "Taking a global and collaborative approach is both bold and forward-thinking. By coming together, investing in research, and improving our knowledge of neuroinflammation, we will improve diagnosis and prevention, discover new treatments, and, crucially, find cures." Why Neuroinflammation? Inflammation is the immune system's natural response to injury, illness, and infection. Neuroinflammation—an inflammatory immune response in the brain and spinal cord—plays a role in brain health at all stages of life, from fetal development to aging, and contributes to the formation of nearly every brain disease. Understanding both the protective and detrimental effects of neuroinflammation will allow doctors to more precisely target diseases as varied as Alzheimer's disease and other dementias, stroke, Parkinson's disease, ALS, MS, encephalitis, and COVID-19-associated brain disease. Together, these diseases affect 60% of the U.S. population and at least 3 billion people worldwide, and they attack the essence of what makes us human: thought, speech, emotion, and movement. "We believe in the 'Cure One, Cure Many' ethos of the American Brain Foundation," said donors from a private family foundation that made a $2.2 million donation to the initiative. "This is why we felt it was important to make an investment in the innovative neuroinflammation initiative, which will shed light on a mechanism that is present in almost every brain disease and neurologic condition." Driving Research Advancements Across Multiple Brain Diseases The American Brain Foundation will make phase 1 grants from an initial pool of $5 million in 2025 as it raises an additional $5 million for phase 2 grants. Phase 2 will be an opportunity for the Foundation and its partners to fund new projects and to provide follow-up funding to the most promising Phase 1 projects to advance translation. "We are very pleased to support this novel initiative, which has the potential to uncover common mechanisms across many different brain diseases and disorders of the nervous system, including multiple sclerosis," said Dr. Bruce Bebo, executive vice president of research at the National MS Society. "This venture holds promise for identifying new pathways to stop destructive immune activity in millions of people living with these disorders." The American Brain Foundation will begin soliciting research proposals for the neuroinflammation initiative in spring 2024, and research will begin in 2025. To learn more about the neuroinflammation initiative and other currently funded research, visit AmericanBrainFoundation.org. About the American Brain Foundation The American Brain Foundation promotes and invests in research across the whole spectrum of brain diseases and disorders knowing that when we find a cure for one brain disease, we will find cures for many. Our holistic approach focuses on building bridges between different brain diseases to break new ground in both research and application. Media Contact Emily Christian [email protected] 612-928-6319 SOURCE American Brain Foundation

Surge in number of patients affected from neurological disorders drives the growth of the global deep brain stimulation devices market. Based on region, North America contributed the highest share in 2018, and will maintain its dominance throughout the forecast period. Deep Brain Stimulation Devices Market generated $881.9 million in 2018, and is estimated to reach $2.80 billion by 2026, registering a CAGR of 15.5% from 2019 to 2026. The report offers an extensive analysis of changing market dynamics, key winning strategies, business performance, major segments, and competitive scenarios. Surge in number of patients affected by neurological disorders and increase in neurological R&D activities drive the growth of the global deep brain stimulation devices market. However, side effects and risks related to deep brain stimulation hinders the market growth. Furthermore, implementation of deep brain stimulators for different applications is expected to present new opportunities for market players in near future. Request for Sample Report for More Insights@ Covid-19 scenario: Deep brain stimulation devices manufacturing companies have been affected to a larger extent due to disrupted supply chain during the Covid-19 outbreak. In addition, most hospitals have been postponing selected procedures and non-urgent clinic visits to conserve hospital resources to treat Covid-19 infected patients and avoid transmission. Due to this, the demand for deep brain stimulation devices has been declined. The report offers a detailed segmentation of the global deep brain stimulation devices market based on application, end-user, and region. Based on application, the dystonia segment contributed to the largest share in 2018, accounting for nearly one-sixth of the total share, and is estimated to maintain its dominant position during the forecast period. The research also analyzes segments including parkinson’s disease, essential tremor, epilepsy, obsessive compulsive disorder, and others. Based on end user, the neurological clinics segment is expected to register the highest CAGR of 15.2% from 2019 to 2026. The report also discusses segment such as hospitals, ambulatory surgical centers, and others. Based on region, North America contributed the highest share, accounting for nearly two-fifths of the total market share in 2018, and will maintain its dominance throughout the forecast period. However, Asia-Pacific is expected to grow at the highest CAGR of 19.2% from 2019 to 2026. Leading market players analyzed in the research include Aleva Neurotherapeutics SA, Abbott Laboratories, Functional Neuromodulation Ltd., Boston Scientific Corporation, Medtronic plc, Beijing PINS Medical Co., Ltd., Nevro Corporation, NeuroPace Inc., and Neuronetics Inc.. Key Market Segments: By Application:- Parkinson's Disease Epilepsy Essential Tremor Dystonia Obsessive Compulsive Disorder Others By End User:- Hospitals Ambulatory Surgical Centers Neurological Clinics Others By Region:- North America Europe Asia-Pacific Trending Reports of Healthcare: Tissue Ablation Market - Global Opportunity Analysis and Industry Forecast, 2019-2028 Ultrasonic Scalpel Market - Global Opportunity Analysis and Industry Forecast, 2019-2028 About Us: Allied Market Research (AMR) is a full-service market research and business-consulting wing of Allied Analytics LLP based in Portland, Oregon. Allied Market Research provides global enterprises as well as medium and small businesses with unmatched quality of "Market Research Reports" and "Business Intelligence Solutions." AMR has a targeted view to provide business insights and consulting to assist its clients to make strategic business decisions and achieve sustainable growth in their respective market domain. We are in professional corporate relations with various companies and this helps us in digging out market data that helps us generate accurate research data tables and confirms utmost accuracy in our market forecasting. Allied Market Research CEO Pawan Kumar is instrumental in inspiring and encouraging everyone associated with the company to maintain high quality of data and help clients in every way possible to achieve success. Each and every data presented in the reports published by us is extracted through primary interviews with top officials from leading companies of domain concerned. Our secondary data procurement methodology includes deep online and offline research and discussion with knowledgeable professionals and analysts in the industry. Contact: David Correa 5933 NE Win Sivers Drive #205, Portland, OR 97220 United States USA/Canada (Toll Free): +1-800-792-5285, +1-503-894-6022, +1-503-446-1141 UK: +44-845-528-1300 Hong Kong: +852-301-84916 India (Pune): +91-20-66346060 Fax: +1(855)550-5975 help@alliedmarketresearch (dot) com