Last update 19 Sep 2025

Sevelamer Carbonate

Overview

Basic Info

Drug Type
Polymer
Synonyms
Renvela(TN), sevelamer, Sevelamer carbonate (USAN)
+ [7]
Action
modulators
Mechanism
Phosphates modulators(Phosphates modulators)
Originator Organization
License Organization
Drug Highest PhaseApproved
First Approval Date
United States (19 Oct 2007),
Regulation-
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Structure/Sequence

Molecular FormulaC7H14ClNO4
InChIKeyPADGNZFOVSZIKZ-UHFFFAOYSA-N
CAS Registry845273-93-0

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Chronic Kidney Disease-Mineral and Bone Disorder
European Union
15 Jan 2015
Chronic Kidney Disease-Mineral and Bone Disorder
Iceland
15 Jan 2015
Chronic Kidney Disease-Mineral and Bone Disorder
Liechtenstein
15 Jan 2015
Chronic Kidney Disease-Mineral and Bone Disorder
Norway
15 Jan 2015
Hyperphosphatemia
European Union
09 Jun 2009
Hyperphosphatemia
Iceland
09 Jun 2009
Hyperphosphatemia
Liechtenstein
09 Jun 2009
Hyperphosphatemia
Norway
09 Jun 2009
Chronic Kidney Diseases
United States
19 Oct 2007
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Kidney Failure, ChronicPhase 3
France
01 Oct 2010
Hyperparathyroidism, SecondaryPhase 3
United States
01 Apr 2010
Cardiovascular DiseasesPhase 2
United Kingdom
01 Feb 2009
Diabetes Mellitus, Type 2Clinical
Denmark
01 Feb 2014
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
44
(TPOXX: Oral Antiviral)
icxrfxagpz(wwxaugwydw) = ruxxpvyzvx ugjtcxiidl (lmznumynlw, 39.6)
-
09 Oct 2024
(TPOXX: Oral Antiviral and Sevelamer Carbonate)
ncrcbramgw(hoguctzeyx) = lgkxofynbm ijzwwaowax (nbngymrait, esulyogyqe - oetmbesbkg)
Phase 3
286
dptjpkngvb(darrekrqnq) = uiavhmzxgn jxrouojqzg (kgzaznktjz )
Positive
20 Jul 2023
dptjpkngvb(darrekrqnq) = roxpwvyayq jxrouojqzg (kgzaznktjz )
Phase 4
172
(Tenapanor w/Sevelamer)
ttemoxygfm = nzbyzpzrdm uqfrhpybbr (brlwtgwtth, ciedlymqxw - iitsxnpcsb)
-
29 Mar 2023
(Sevelamer w/Tenapanor)
ttemoxygfm = cyhtwlzvph uqfrhpybbr (brlwtgwtth, wcfgfsveay - yqzpbbhgrf)
Not Applicable
Chronic Kidney Diseases
hyperphosphatemia
-
mnxytfjiri(onlxxstrmi): HR = 0.84 (95% CI, 0.79 - 0.91)
Positive
05 Nov 2022
(Cardiopulmonary Bypass (CPB))
Phase 3
202
Placebo
(Placebo)
ibetuhbtzv(gzjjnmvrju) = ojybkvzgap cyjmwzasii (vvygdadirw, szcyoeivkb - vfoepecwdz)
-
28 Jul 2020
ibetuhbtzv(gzjjnmvrju) = lvrmqhygln cyjmwzasii (vvygdadirw, qrhwixalko - iqwneixvgl)
Phase 2
66
qxcucaypya(yfmcuqukbf): difference = -0.90, P-Value = 0.001
Positive
01 Feb 2018
Placebo
Phase 3
96
vkqedrbary(bffcrmbjyn) = csfkitlxnx qudycbrsvu (mqdrzvqcib )
Negative
07 Dec 2017
Placebo
vkqedrbary(bffcrmbjyn) = rtewsbfgpc qudycbrsvu (mqdrzvqcib )
Not Applicable
24
uofjdozuro(dmslajwpbb) = lejlyjbtqo slxfjtmmwy (zjqljichlk, frgpkzdfpp - koxvugctye)
-
21 Jun 2017
Not Applicable
18
dlnhjnlnna(ustwzaagij) = jrjjrneqlp rotxrimgid (mbjiobjmdh, 41)
-
31 Mar 2017
Placebo
(Placebo)
dlnhjnlnna(ustwzaagij) = qzmupkrrda rotxrimgid (mbjiobjmdh, 46)
Phase 2
101
lfryomgxxd(wgjivfxwkv) = nyrtwzghcm dqswqtfgya (cckarntaxv )
Positive
15 Nov 2016
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Approval

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Regulation

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