The study aims to investigate whether behavioral interventions promote cessation in adult smokers by ameliorating negative emotions and improving self-control and identify the neural markers of these effects.

Start Date01 Dec 2024

Sponsor / Collaborator

Yale University

[+1]

NCT06637358 / Not yet recruitingNot ApplicableIIT

A Text-based Reduction Intervention for Smokeless Tobacco Cessation- Pilot Study

All participants will receive the EnufSnuff.TXT scheduled gradual reduction (SGR) intervention for 6 weeks and, for those who do not reach the point of quit, includes getting randomized (like the flip of a coin) into either an additional 8-10 weeks of the EnufSnuff.TXT intervention or into receiving an additional 8-10 weeks of the EnufSnuff.TXT intervention along with a dedicated text quit coach to send and receive live support.

Start Date01 Nov 2024

Sponsor / Collaborator

Duke University Medical Center

NCT06483412 / Not yet recruitingNot ApplicableIIT

Evaluation Tobacco Prevention Toolkit Healthy Futures: Alternative-to-Suspension Vaping Intervention

The Healthy Futures: Alternative-to-Suspension Curriculum is a free, online curriculum developed to educate students and provide them with resources to quit tobacco/nicotine use. The investigation aims to estimate the extent to which Healthy Futures: Alternative-to-Suspension changes high school student's knowledge of, attitudes towards, intentions to use, and actual use of tobacco/nicotine.

Start Date01 Oct 2024

Sponsor / Collaborator

Stanford University

100 Clinical Results associated with Tobacco Use Cessation

100 Translational Medicine associated with Tobacco Use Cessation

0 Patents (Medical) associated with Tobacco Use Cessation

Literatures (Medical) associated with Tobacco Use Cessation

01 Dec 2010·Addictive BehaviorsQ2 · MEDICINE

A quantitative analysis of subjective, cognitive, and physiological manifestations of the acute tobacco abstinence syndrome

Q2 · MEDICINE

Article

Author: Stephen J. Heishman ; Adam M. Leventhal ; Andrew J. Waters ; Wallace B. Pickworth ; Eric T. Moolchan

RATIONALEPrevious studies have documented the existence of signs and symptoms of the acute tobacco abstinence syndrome; however, less attention has been paid to quantifying the magnitude of these effects.OBJECTIVEThe present study quantified the relative magnitude of subjective, cognitive, and physiological manifestations of acute tobacco abstinence.METHODSmokers (N=203, ≥ 15 cig/day) attended two counterbalanced laboratory sessions, one following 12-h of abstinence and the other following ad-lib smoking. At both sessions, they completed an extensive battery of self-report measures (withdrawal, affect, hunger, craving, subjective attentional bias towards smoking cues), physiological assessments (heart rate, blood pressure, brain EEG), and cognitive performance tasks (psychomotor processing, sustained attention, objective attentional bias).RESULTSAbstinence effects were largest for craving, subjective attentional bias, negative affect, overall withdrawal severity, concentration difficulty, hunger, and heart rate. Effects were moderate for positive affect and EEG power. Effects were small, but reliable, for psychomotor speed, sustained attention, and somatic symptoms. Effects on performance-based indices of attentional bias towards smoking-related cues were small and reliable for some indices but not others. Effects were small and inconsistent for blood pressure and EEG frequency. Variation in internal consistency accounted for 33% of the variation in abstinence effect sizes across measures.CONCLUSIONSThere was a wide range of effect sizes both across and within domains, indicating that the acute tobacco abstinence syndrome is not a monotonic phenomenon. These findings may be indicative of the relative magnitudes of signs and symptoms that the average smoker may exhibit during acute abstinence.

Journal of Abnormal PsychologyQ2 · PSYCHOLOGY

Pain as a predictor and consequence of tobacco abstinence effects amongst African American smokers.

Q2 · PSYCHOLOGY

Article

Author: Leventhal, Adam M ; Kirkpatrick, Matthew G ; McBeth, Julia F ; Ditre, Joseph W ; Dunn, Kelly E ; Ray, Lara A ; Bello, Mariel S

African Americans are subject to health disparities in smoking and chronic pain. Given that nicotine has analgesic properties, increases in acute pain may be an expression of the tobacco abstinence syndrome, particularly among African American smokers with chronic pain. This report is a secondary analysis of data from an ongoing study of individual differences in laboratory-derived tobacco abstinence phenotypes in African American smokers. We tested whether overnight smoking abstinence increased acute pain and whether abstinence-induced changes in acute pain were correlated with other expressions of tobacco abstinence and amplified among smokers with chronic pain. African American smokers (N = 214; 10+ cig/day) attended a baseline visit (when chronic pain was reported), and two counterbalanced experimental sessions (ad libitum smoking vs. 16-hr smoking abstinence). At both experimental sessions, measures of self-reported acute pain and other tobacco abstinence symptoms were administered. Smoking abstinence significantly increased acute pain (d = .17, p = .01). Correlations between abstinence-induced changes in acute pain and abstinence-induced changes in negative affect, r = .15, p = .02, smoking urges, r = .13, p = .05, and composite nicotine withdrawal symptoms, r = .13, p = .06, were small and nonsignificant after correction for multiple tests, indicating that phenotypic variation in abstinence-provoked changes in acute pain and other tobacco abstinence expressions were largely independent. Baseline levels of chronic pain predicted greater abstinence-induced pain amplification at experimental sessions (βs = .29-.31; ps < .001). Acute pain is greater following overnight tobacco abstinence (vs. satiation) among African American smokers, predominantly among those with chronic pain. Addressing pain in tobacco addiction science, treatment, and health equity programming warrants consideration. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Revista de sanidad e higiene publica

[Symptomatology of the tobacco abstinence syndrome].

Article

Author: Sabate Cosellas, F

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