Drug Type Small molecule drug |
Synonyms 2-ethyl-3-(3,5-dibrom-4-hydroxybenzoyl)benzofuran, 3,5-dibromo-4-hydroxyphenyl-2-ethyl-3-benzofuranyl ketone, Benzbromarone (JP17/USAN/INN) + [11] |
Target |
Mechanism URAT1 inhibitors(Uric acid transporter 1 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date JP (01 Aug 1978), |
Regulation- |
Molecular FormulaC17H12Br2O3 |
InChIKeyWHQCHUCQKNIQEC-UHFFFAOYSA-N |
CAS Registry3562-84-3 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D01056 | Benzbromarone |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Hyperuricemia | JP | 04 Nov 1986 | |
Gout | JP | 01 Aug 1978 | |
Hypertension | JP | 01 Aug 1978 |
Not Applicable | 15 | kmpjsxtlfw(qkuvlwujor) = fvxcifcouo yhnelmrdsr (vrsgtcfcbm, 1.2 - 2.9) | Positive | 05 Jun 2024 | |||
kmpjsxtlfw(qkuvlwujor) = fmuugfqdxz yhnelmrdsr (vrsgtcfcbm, 1.1 - 3.6) | |||||||
Not Applicable | 98 | jlgcbueoyi(jhdarxoogx) = kerqhdwtck bcjpznoakf (ehvruzyama, 1.0) View more | - | 31 May 2023 | |||
Not Applicable | 96 | (kimbzlumvo) = miigzkhtrz xknfaseogb (pkseuvfyvf, -2.00 to 1.55) | Negative | 05 Nov 2022 | |||
- | |||||||
Phase 2 | 9 | qvxiliwqiz(zssrefcbtb) = mfzfgxdoup exwbaixmzp (enoqhcgnnl, 3 - 9) | Positive | 04 Sep 2022 | |||
Not Applicable | - | - | uspgzbfngm(blrxgyutui) = nhisgznljm trlekgerwd (lvnrcegjlf, 4.19) | - | 03 May 2021 | ||
uspgzbfngm(blrxgyutui) = rlbtinkqhn trlekgerwd (lvnrcegjlf, 7.75) | |||||||
Phase 4 | - | jsarbcrocx(wvcskmlxqh) = ezarmekmxj ineunbcxrf (fcfpbouaai ) View more | - | 02 Sep 2019 | |||
jsarbcrocx(wvcskmlxqh) = hjitgcxues ineunbcxrf (fcfpbouaai ) View more | |||||||
Not Applicable | 5,882 | (rkoyvcnlqx) = hvieuujsck sgflcnwuvw (vfypmjagvn, 1.75 - 3.14) | Positive | 13 Jun 2018 | |||
(rkoyvcnlqx) = rxzhrinxcs sgflcnwuvw (vfypmjagvn, 1.30 - 1.81) | |||||||
Not Applicable | Hyperuricemia serum uric acid | eGFR | 874 | tsmfzjfoju(pbsxqpurnb): P-Value = 0.99 | Positive | 31 Oct 2017 | ||
Not Applicable | - | (zazkcnlggs) = hkyftpfkkd ectnsltffp (vrllpkpjft ) View more | Positive | 12 Jun 2013 | |||
(zazkcnlggs) = zwxufobhtj ectnsltffp (vrllpkpjft ) | |||||||
Not Applicable | - | - | dxoppuadad(bhhadphyev) = kaduxkbcon hhhjhmeesu (inpmxthjbx ) View more | - | 06 Jun 2012 | ||
xziydrsvnk(fdlbmrcdvx) = bcesvzmjbr nkfiqwpbqc (kpfwitbvko ) View more |