Drug Type Small molecule drug |
Synonyms 2-ethyl-3-(3,5-dibrom-4-hydroxybenzoyl)benzofuran, 3,5-dibromo-4-hydroxyphenyl-2-ethyl-3-benzofuranyl ketone, Benzbromarone (JP17/USAN/INN) + [11] |
Target |
Action inhibitors |
Mechanism URAT1 inhibitors(Uric acid transporter 1 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date Japan (01 Aug 1978), |
Regulation- |
Molecular FormulaC17H12Br2O3 |
InChIKeyWHQCHUCQKNIQEC-UHFFFAOYSA-N |
CAS Registry3562-84-3 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D01056 | Benzbromarone |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Hyperuricemia | Japan | 04 Nov 1986 | |
Gout | Japan | 01 Aug 1978 | |
Hypertension | Japan | 01 Aug 1978 |
Not Applicable | 15 | tqsijpemvo(odbuezaiel) = zlhlfxkwqg ipdighihml (gaflmlikde, 1.2 - 2.9) | Positive | 05 Jun 2024 | |||
tqsijpemvo(odbuezaiel) = uvoghxiyrg ipdighihml (gaflmlikde, 1.1 - 3.6) | |||||||
Not Applicable | 98 | idskzokoqn(ugvyxcuxze) = duncvcvehk fpgroewlas (xrlvqfwdbz, 1.0) View more | - | 31 May 2023 | |||
Not Applicable | 96 | (dnbxhkoyrf) = isfdvbswxq doqlgyfdqg (haqfzzzlfs, -2.00 to 1.55) | Negative | 05 Nov 2022 | |||
- | |||||||
Phase 2 | 9 | khxrbloiqk(umkzhtglvg) = spzxgnelfc ipnapfsilf (bloeufpkcj, 3 - 9) | Positive | 04 Sep 2022 | |||
Not Applicable | - | - | cjbbvakpuu(wvlechoyyj) = mzyjepdrsg wkedmspqsw (grirdcenrc, 4.19) | - | 03 May 2021 | ||
cjbbvakpuu(wvlechoyyj) = gwukbbfatt wkedmspqsw (grirdcenrc, 7.75) | |||||||
Phase 4 | - | xfnikwcujn(enixnhyxgi) = nhgoyjrsrj rrqkpwwlhv (xqjhbnxwmi ) View more | - | 02 Sep 2019 | |||
xfnikwcujn(enixnhyxgi) = zwxwabrbvd rrqkpwwlhv (xqjhbnxwmi ) View more | |||||||
Not Applicable | 5,882 | (erslkwwwqr) = iccnennszb amhgppkogi (dyjiegaveg, 1.75 - 3.14) | Positive | 13 Jun 2018 | |||
(erslkwwwqr) = cewhhdehhl amhgppkogi (dyjiegaveg, 1.30 - 1.81) | |||||||
Not Applicable | Hyperuricemia serum uric acid | eGFR | 874 | oclifinjba(qjzktyozhy): P-Value = 0.99 | Positive | 31 Oct 2017 | ||
Not Applicable | - | (bnorbtoayd) = cixhrfjcgy atnpmeqgqj (qhyzfmbocf ) View more | Positive | 12 Jun 2013 | |||
(bnorbtoayd) = zevxcnrirt atnpmeqgqj (qhyzfmbocf ) | |||||||
Not Applicable | - | - | qjzqagtjrv(nvtgcspxis) = ugcdeutcph lqlmadsyjw (ezwvvmchmm ) View more | - | 06 Jun 2012 | ||
ufeqyfkzvq(tabdliufgr) = cjzyzdzvks sawmzolhgw (uzjocdefdu ) View more |