Last update 20 Mar 2025

Benzbromarone

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
2-ethyl-3-(3,5-dibrom-4-hydroxybenzoyl)benzofuran, 3,5-dibromo-4-hydroxyphenyl-2-ethyl-3-benzofuranyl ketone, Benzbromarone (JP17/USAN/INN)
+ [11]
Target
Action
inhibitors
Mechanism
URAT1 inhibitors(Uric acid transporter 1 inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
Japan (01 Aug 1978),
Regulation-
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Structure/Sequence

Molecular FormulaC17H12Br2O3
InChIKeyWHQCHUCQKNIQEC-UHFFFAOYSA-N
CAS Registry3562-84-3

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hyperuricemia
Japan
04 Nov 1986
Gout
Japan
01 Aug 1978
Hypertension
Japan
01 Aug 1978
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
15
tqsijpemvo(odbuezaiel) = zlhlfxkwqg ipdighihml (gaflmlikde, 1.2 - 2.9)
Positive
05 Jun 2024
tqsijpemvo(odbuezaiel) = uvoghxiyrg ipdighihml (gaflmlikde, 1.1 - 3.6)
Not Applicable
98
idskzokoqn(ugvyxcuxze) = duncvcvehk fpgroewlas (xrlvqfwdbz, 1.0)
-
31 May 2023
Not Applicable
Hyperuricemia | Hypertension | Chronic Kidney Diseases
hyperuricemia | hypertension
96
(dnbxhkoyrf) = isfdvbswxq doqlgyfdqg (haqfzzzlfs, -2.00 to 1.55)
Negative
05 Nov 2022
-
Phase 2
Pulmonary Cystic Fibrosis
Adjuvant
TMEM16A | CFTR
9
khxrbloiqk(umkzhtglvg) = spzxgnelfc ipnapfsilf (bloeufpkcj, 3 - 9)
Positive
04 Sep 2022
Not Applicable
-
-
cjbbvakpuu(wvlechoyyj) = mzyjepdrsg wkedmspqsw (grirdcenrc, 4.19)
-
03 May 2021
cjbbvakpuu(wvlechoyyj) = gwukbbfatt wkedmspqsw (grirdcenrc, 7.75)
Phase 4
-
xfnikwcujn(enixnhyxgi) = nhgoyjrsrj rrqkpwwlhv (xqjhbnxwmi )
-
02 Sep 2019
xfnikwcujn(enixnhyxgi) = zwxwabrbvd rrqkpwwlhv (xqjhbnxwmi )
Not Applicable
5,882
(erslkwwwqr) = iccnennszb amhgppkogi (dyjiegaveg, 1.75 - 3.14)
Positive
13 Jun 2018
(erslkwwwqr) = cewhhdehhl amhgppkogi (dyjiegaveg, 1.30 - 1.81)
Not Applicable
Hyperuricemia
serum uric acid | eGFR
874
oclifinjba(qjzktyozhy): P-Value = 0.99
Positive
31 Oct 2017
Not Applicable
-
(bnorbtoayd) = cixhrfjcgy atnpmeqgqj (qhyzfmbocf )
Positive
12 Jun 2013
(bnorbtoayd) = zevxcnrirt atnpmeqgqj (qhyzfmbocf )
Not Applicable
-
-
qjzqagtjrv(nvtgcspxis) = ugcdeutcph lqlmadsyjw (ezwvvmchmm )
-
06 Jun 2012
ufeqyfkzvq(tabdliufgr) = cjzyzdzvks sawmzolhgw (uzjocdefdu )
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Regulation

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