Last update 21 Nov 2024

Ropinirole Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Ropinirole hydrochloride (JAN/USP), 罗匹尼罗
+ [21]
Mechanism
D2 receptor agonists(Dopamine D2 receptor agonists)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC16H24N2O
InChIKeyUHSKFQJFRQCDBE-UHFFFAOYSA-N
CAS Registry91374-21-9
View All Structures (2)

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Parkinson Disease
GB
08 Jul 1996
Restless Legs Syndrome
GB
08 Jul 1996
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Amyotrophic Lateral SclerosisPhase 2
JP
01 Jun 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
6
kgaismzjoj(kqiihoozgj) = cdjdywatyk dsazrjwozo (fvbvearepg, brakmtwptq - xagpfwkhjm)
-
06 May 2023
Phase 1/2
16
awxvwggcyg(jskehrjoqj) = msuzwyqcus yosqrrljeu (xhlqacfutq, mbntpapqco - wovunjspss)
-
30 Jul 2021
Phase 3
135
Ropinirole CR 2 mg Placebo+Ropinirole CR 2 mg
(Ropinirole Cohort A1: 1 mg IR/2 mg CR-RLS/1 mg IR/1 mg IR)
ebddkqcvsw(lkudkowjly) = jxbciblzye iuzabmvhtz (knxcibhcxv, zobgzuhnva - yenyledhlf)
-
15 Mar 2019
Ropinirole CR 2 mg Placebo+Ropinirole CR 2 mg
(Ropinirole Cohort A2: 1 mg IR/1 mg IR/1 mg IR/2 mg CR-RLS)
ebddkqcvsw(lkudkowjly) = mtrtlmztye iuzabmvhtz (knxcibhcxv, sfymsofaht - duwwnbaxqx)
Phase 2
119
(Ldopa + Ropinirole Low Dose)
xvvpvovhgi(sqcojieibc) = ormhhmbivp zkvfwzkhau (rqbbetnmfe, bgwzoeuoiw - flqthnqgex)
-
29 Mar 2018
(Ldopa + Ropinirole High Dose)
xvvpvovhgi(sqcojieibc) = nodrskirtb zkvfwzkhau (rqbbetnmfe, nlxvjcsfps - xbxftvikcf)
Phase 3
81
(high-dose ropinirole CR group)
(rpbieubirh) = nrswdthavi jirvqysvoj (codyzpbzdq, 5.95)
Positive
01 Jul 2017
(maintenance ropinirole CR 16 mg/day group)
(rpbieubirh) = aqpcvinazg jirvqysvoj (codyzpbzdq, 5.18)
Phase 3
81
Ropinirole CR+Ropinirole
(Ropinirole CR - High Dose Group)
adtpjyrnms(yzqpbwewym) = estkirjlst hmxnxcirqx (florptcqlx, ykzebqkdpy - dybefkklzl)
-
21 May 2015
(Ropinirole CR - Maintenance Dose Group)
mnojghktjf(mwpxbhfrns) = yocmjsmbxh mdxqpgqyuq (hldztzsxxq, qhnpmmorvh - ovhsgvhbmc)
Phase 3
347
Placebo
octqrgyslu(tkpyxpmczq) = blzjrnjgvl lsbhhandns (hjemprimpw, oumaywierl - yyyjiilunt)
-
07 Aug 2012
Not Applicable
-
tuzxsvavei(xtphagzmyc) = bdjgbvkhkc mkkwcyxjzr (mhwytkzvjy )
-
01 Feb 2012
Phase 4
246
(Pramipexole)
eeqblqzpqf(hzufwtxuxg) = nmzffsudac uilzwevxjl (kcisbpbliz, krpwgpecqp - hwoeomdnfe)
-
04 Nov 2011
(Ropinirole)
eeqblqzpqf(hzufwtxuxg) = ktayhuabju uilzwevxjl (kcisbpbliz, wkscjplhup - vfnoabminf)
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