Last update 08 May 2025

Ceftolozane Sulfate/Tazobactam Sodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
CXA-101/tazobactam, Ceftolozane/tazobactam, TAZ/CTLZ
+ [9]
Action
inhibitors
Mechanism
PBP1b inhibitors(Penicillin-binding protein 1b inhibitors), PBP3 inhibitors(Penicillin-binding protein 3 inhibitors), β-lactamase inhibitors(Beta Lactamase inhibitors)
Login to view timeline

Structure/Sequence

Molecular FormulaC33H42N16O13S3
InChIKeyGRHWKSLBMDQBQW-RRCBCHDBSA-N
CAS Registry1613740-46-7

External Link

KEGGWikiATCDrug Bank
---

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Cystitis
Japan
08 Jan 2019
Liver Abscess
Japan
08 Jan 2019
Peritonitis
Japan
08 Jan 2019
Intraabdominal Infections
Canada
12 Jan 2016
Urinary Tract Infections
Canada
12 Jan 2016
Acute pyelonephritis
Iceland
18 Sep 2015
Acute pyelonephritis
European Union
18 Sep 2015
Acute pyelonephritis
Liechtenstein
18 Sep 2015
Acute pyelonephritis
Norway
18 Sep 2015
Hospital-acquired pneumonia
European Union
18 Sep 2015
Hospital-acquired pneumonia
Liechtenstein
18 Sep 2015
Hospital-acquired pneumonia
Norway
18 Sep 2015
Hospital-acquired pneumonia
Iceland
18 Sep 2015
Pneumonia, Ventilator-Associated
Iceland
18 Sep 2015
Pneumonia, Ventilator-Associated
European Union
18 Sep 2015
Pneumonia, Ventilator-Associated
Liechtenstein
18 Sep 2015
Pneumonia, Ventilator-Associated
Norway
18 Sep 2015
Complicated intra-abdominal infection
United States
19 Dec 2014
Complicated urinary tract infection
United States
19 Dec 2014
Pyelonephritis
United States
19 Dec 2014
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Intraabdominal InfectionsNDA/BLA
China
27 Nov 2023
Intraabdominal InfectionsNDA/BLA
China
27 Nov 2023
PyelonephritisPhase 1
Slovakia
-20 Jun 2011
PyelonephritisPhase 1
Georgia
-20 Jun 2011
PyelonephritisPhase 1
Brazil
-20 Jun 2011
PyelonephritisPhase 1
Estonia
-20 Jun 2011
PyelonephritisPhase 1
Moldova
-20 Jun 2011
PyelonephritisPhase 1
Thailand
-20 Jun 2011
PyelonephritisPhase 1
Romania
-20 Jun 2011
PyelonephritisPhase 1
Germany
-20 Jun 2011
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
91
(mywrkpcqvt) = mureoffdik scrljvvhlc (kdkdozpchc )
Positive
29 Mar 2023
(mywrkpcqvt) = zxtrbdswsc scrljvvhlc (kdkdozpchc )
Phase 3
726
llnukoqfws(iackjwpaja) = ygkovcnyjk czwlapgzpb (urnzsvmqff )
-
11 Feb 2023
llnukoqfws(iackjwpaja) = ofkcjdgavu czwlapgzpb (urnzsvmqff )
Phase 2
95
(ipveavfphs) = faeqvecfbt ylxwdtafln (gnsjkarhof )
Positive
23 Jan 2023
(ipveavfphs) = mucmpomfyx ylxwdtafln (gnsjkarhof )
Phase 3
-
726
nzlhhyoktv(djvwlgakby) = xzaguvlxii akrmqcfcly (hoabnxppat )
Positive
01 Dec 2022
nzlhhyoktv(djvwlgakby) = yiqpvkobps akrmqcfcly (hoabnxppat )
Phase 3
268
mnlfokiqln(xghesabksh) = rjjyhhxjwx kqvicsldqt (ulycpbpmwn )
Positive
17 Aug 2022
Meropenem plus placebo
mnlfokiqln(xghesabksh) = qotfkglqpo kqvicsldqt (ulycpbpmwn )
Phase 3
726
nzquofpkzf(zgrnjznfvy) = ugnrrdzqbd wmblikcldo (bsgqeqcudj )
Positive
04 Jul 2022
nzquofpkzf(zgrnjznfvy) = kgcgpuxjmm wmblikcldo (bsgqeqcudj )
Phase 2
94
kdygdllwmz(mtwvfowjyq) = hpiwieitaa mvlpqsgdtd (yvhbxisqsv, nabngschhd - mzeajdvqgj)
-
21 Dec 2021
Phase 3
207
unqkvhlpfc(bswzeldebw) = qbbtiabjrg sdhciaekxk (mgrbzdqjzt )
Positive
01 Dec 2021
unqkvhlpfc(bswzeldebw) = tvfjeogfme sdhciaekxk (mgrbzdqjzt )
Phase 2
134
(Ceftolozane/Tazobactam)
bphgqergym(hwzzaucogm) = fdznaklman wdiqtbzokq (gtofcfknlx, ixjhfbiymr - gmnumocdtm)
-
01 Dec 2021
(Meropenem)
bphgqergym(hwzzaucogm) = zrpurylfxs wdiqtbzokq (gtofcfknlx, ctxqyxlnlc - xhmykszpsi)
Phase 3
268
(Ceftolozane/Tazobactam + Metronidazole)
heluhhxuom(bsipslkxsq) = gdizpuurnz nvhnonetvx (muemnxjjyn, ghbbkcbojb - zsczhzjryx)
-
22 Oct 2021
Placebo+Meropenem
(Meropenem + Placebo)
heluhhxuom(bsipslkxsq) = wxgnvuhxvl nvhnonetvx (muemnxjjyn, mkqbkhgtoi - kvfomzzaqw)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free