Organon Pharma (UK) Ltd.

To evaluate the pharmacokinetic (PK) characteristics of ceftolozane/tazobactam after single and multiple doses in healthy Chinese subjects. To evaluate the safety and tolerability of ceftolozane/tazobactam after single and multiple doses in healthy Chinese subjects.

To evaluate the pharmacokinetic profiles, safety, and tolerability of atorvastatin (and metabolites) and ezetimibe (and total ezetimibe) in healthy Chinese subjects after single and multiple oral administration of MK-0653C 10 mg/10 mg and 10 mg/20 mg.

To determine whether MK-0653C (ezetimibe/atorvastatin combination tablets) 10/10 mg or 10/20 mg is superior to double-dose atorvastatin in lowering LDL-C in subjects with hypercholesterolemia that is not adequately controlled on statin monotherapy.