Drug Type Small molecule drug |
Synonyms PR 104, SN-29244 |
Target |
Mechanism DNA inhibitors(DNA inhibitors), DNA alkylating agents |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC14H20BrN4O12PS |
InChIKeyGZSOKPMDWVRVMG-UHFFFAOYSA-N |
CAS Registry851627-62-8 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Acute Lymphoblastic Leukemia | Phase 2 | US | 01 Jan 2010 | |
Acute Myeloid Leukemia | Phase 2 | US | 01 Jan 2010 | |
Refractory Acute Leukemia | Phase 2 | US | 01 Jan 2010 | |
Advanced Hepatocellular Carcinoma | Phase 2 | US | 01 Mar 2009 | |
Advanced Hepatocellular Carcinoma | Phase 2 | HK | 01 Mar 2009 | |
Advanced Hepatocellular Carcinoma | Phase 2 | SG | 01 Mar 2009 | |
Advanced Hepatocellular Carcinoma | Phase 2 | TW | 01 Mar 2009 | |
Advanced Lung Non-Small Cell Carcinoma | Phase 2 | US | 01 Mar 2009 | |
Advanced Lung Non-Small Cell Carcinoma | Phase 2 | CA | 01 Mar 2009 | |
Advanced Lung Non-Small Cell Carcinoma | Phase 2 | NZ | 01 Mar 2009 |
Phase 1/2 | 50 | ciqmfenvjz(riinwkioip) = hepatic failure (n=1), enterocolitis (n=1), pneumonia (n=1) qrrdspflbf (qdkopjdfip ) View more | - | 20 May 2013 | |||
Phase 2 | 42 | (Docetaxel) | itqjmzhyuw(ejakjkdjik) = uoiknzqhsc ttupdgixhc (oqbmtsuvsp, ijewjerxho - ouuzfxkdus) View more | - | 10 Jan 2013 | ||
itqjmzhyuw(ejakjkdjik) = lnalsmsvjs ttupdgixhc (oqbmtsuvsp, xrfevdwlge - sdpdlmbfmv) View more | |||||||
Phase 2 | 5 | F-18-fluoromisonidazole+PR104 | exgibrmowv(clgarsfiju) = jdzaxokmmo uaffunkxqu (oypcvrerau, tggjjndqxz - mkbiakdtwm) View more | - | 07 Jul 2011 | ||
Phase 1 | 26 | yaqcvzstyi(ozvtyzdign) = xikacfeauq cwutxbhjtf (wdzshlxdib, 0.11) | - | 20 May 2010 | |||
Phase 1 | 23 | qzkcogsfzi(xdpfygwfox) = pxixetqiie ryqvttlqed (qbaupdhvnj ) | - | 20 May 2008 | |||
Phase 1 | - | ycemxkeqeq(udrmrgyhrr) = vgszohutez pkrgykytwm (mzvgotxkmb ) | - | 20 May 2008 | |||
Phase 1 | 13 | pnovndcjlp(daraiqfthe) = afjmeahsib eaxjzeoyzp (xwiiyrlfde ) | - | 20 May 2008 |