Last update 07 Nov 2024

Pozanicline Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Pozanicline, Pozanicline Tartrate, A-87089
+ [2]
Mechanism
nAChR α4/β2/α5 agonists(Nicotinic acetylcholine receptor alpha4/beta2/alpha5 agonists), α3β4 receptor antagonists(Neuronal acetylcholine receptor; alpha3/beta4 antagonists), α7 receptor agonists(Neuronal acetylcholine receptor protein alpha-7 subunit agonists)
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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Structure

Molecular FormulaC11H18Cl2N2O
InChIKeyUGVSESCRKJTJAK-XRIOVQLTSA-N
CAS Registry161416-61-1

External Link

KEGGWikiATCDrug Bank
-Pozanicline Hydrochloride-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Attention Deficit Disorder With HyperactivityPhase 2
US
01 Oct 2006
Alzheimer DiseasePhase 2
US
01 Jul 2003
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
17
(ABT-089)
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-
29 Oct 2014
Placebo
(Placebo)
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Clinical Trial

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Approval

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Regulation

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