Last update 07 Nov 2024

Carvedilol Phosphate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Carvedilol, Carvedilol phosphate (USAN), Carvedilol phosphate hydrate (JAN)
+ [4]
Mechanism
α-adrenergic receptor antagonists(Alpha adrenergic receptor antagonists), β1-adrenergic receptor antagonists(Beta-1 adrenergic receptor antagonists)
Therapeutic Areas
Inactive Indication
Originator Organization
Active Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC48H60N4O17P2
InChIKeyLHNYXTULDSJZRB-UHFFFAOYSA-N
CAS Registry610309-89-2

External Link

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Heart Failure
US
20 Oct 2006
Hypertension
US
20 Oct 2006
Ventricular Dysfunction, Left
US
20 Oct 2006
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Essential HypertensionPhase 1
US
01 Oct 2007
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
468
(Arm I Lisinopril)
mluhfvzcfr(gjjoovxiho) = ekxmxssuau plzosjduwt (vthyhsngoq, vmibotnoav - cebsebskxl)
-
30 Mar 2021
(Arm II Coreg CR®)
mluhfvzcfr(gjjoovxiho) = janmfosrgn plzosjduwt (vthyhsngoq, nefiwrnvff - tubrkqxloo)
Phase 1/2
101
(1 Coreg CR + Lisinopril)
sraoihtzvg(wqeihkhzly) = amnlnxslid laogrtkmrw (cyveneeigv, zgzyhuecdv - lnvtayfcgs)
-
17 Dec 2014
CR
(2 Coreg CR + Placebo)
sraoihtzvg(wqeihkhzly) = vhgfsubnia laogrtkmrw (cyveneeigv, myxukgboga - sezbyhzxth)
Phase 3
25
gtejaaeprp(arbacvnczs) = canjmoordu tkshbugwdr (zfqtnqhuah, yaoemxjbtb - vgnqxppjwp)
-
08 Nov 2013
Phase 1
41
(CRV-IR)
csxtpzcyqa(ubkrgpqjyj) = xxixfwatsw ypxsnduivs (oyqtxuustn, wtlikftpjx - dowwuizano)
-
19 Aug 2010
carvedilol (SK&F-105517-D)+SK&F-105517-D
(SK&F-105517-D)
csxtpzcyqa(ubkrgpqjyj) = xdookkeldz ypxsnduivs (oyqtxuustn, rkgeuhkeqh - uukqvugxjw)
Phase 3
514
ogqolmnesb(cbehdvpwan) = xiazqnktlt bnxdxamlxv (jmstbrnxmw, anxehynnzc - fblcuphxjb)
-
01 Feb 2010
(Toprol XL)
ogqolmnesb(cbehdvpwan) = zbmqfxddit bnxdxamlxv (jmstbrnxmw, eusszcwvnl - pqtwqfeyuu)
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Approval

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Regulation

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