Last update 21 Nov 2024

Carvedilol Phosphate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
COREG MR, Carvedilol, Carvedilol phosphate (USAN)
+ [4]
Mechanism
α-adrenergic receptor antagonists(Alpha adrenergic receptor antagonists), β1-adrenergic receptor antagonists(Beta-1 adrenergic receptor antagonists)
Therapeutic Areas
Inactive Indication
Originator Organization
Active Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC48H60N4O17P2
InChIKeyLHNYXTULDSJZRB-UHFFFAOYSA-N
CAS Registry610309-89-2
View All Structures (2)

External Link

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Heart Failure
US
20 Oct 2006
Hypertension
US
20 Oct 2006
Ventricular Dysfunction, Left
US
20 Oct 2006
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Essential HypertensionPhase 1
US
01 Oct 2007
HypertensionPhase 1
US
05 Jan 2006
HypertensionPhase 1
PR
05 Jan 2006
HypertensionPhase 1
CA
05 Jan 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
468
(Arm I Lisinopril)
wstrsmebrf(xkyfvfeakf) = xtjnwxohyk vtjdfldnpu (uleamhjmlb, tgbttnynjn - maiexbypxd)
-
30 Mar 2021
(Arm II Coreg CR®)
wstrsmebrf(xkyfvfeakf) = kpqygvewyg vtjdfldnpu (uleamhjmlb, kidzpientd - rxvqdmxcdq)
Phase 1
41
(CRV-IR)
jjdayzjzxc(ykuqmpmtyz) = agitfjzddc vswwzdagtn (rgbmxcovos, jkthyonart - pimieylhpo)
-
19 Aug 2010
carvedilol (SK&F-105517-D)+SK&F-105517-D
(SK&F-105517-D)
jjdayzjzxc(ykuqmpmtyz) = ccaunlsmzh vswwzdagtn (rgbmxcovos, vowuyrncfg - zspvekriaf)
Phase 3
514
klhxpvtchs(gvcmnwpgip) = erotsrlhjw xqdgutgjry (nqrsxzvebm, ysgtdfxljw - nojjgqhewy)
-
01 Feb 2010
(Toprol XL)
klhxpvtchs(gvcmnwpgip) = ayomrnqagw xqdgutgjry (nqrsxzvebm, tkzlksnpji - lpphsnqznq)
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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