Last update 26 Apr 2025

Dutasteride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Duagen, Dutasteride (JAN/USP/INN), CU-40104
+ [19]
Action
inhibitors
Mechanism
5α-reductase inhibitors(Steroid 5 alpha reductase inhibitors)
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
United States (20 Nov 2001),
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC27H30F6N2O2
InChIKeyJWJOTENAMICLJG-QWBYCMEYSA-N
CAS Registry164656-23-9

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Androgenetic Alopecia
South Korea
12 Dec 2024
Prostatic Hyperplasia
United States
20 Nov 2001
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Localized Prostate CarcinomaPhase 3
United States
01 Nov 2005
Prostatic CancerPhase 3
United States
01 Mar 2003
Prostatic CancerPhase 3
Japan
01 Mar 2003
Prostatic CancerPhase 3
Argentina
01 Mar 2003
Prostatic CancerPhase 3
Australia
01 Mar 2003
Prostatic CancerPhase 3
Austria
01 Mar 2003
Prostatic CancerPhase 3
Belarus
01 Mar 2003
Prostatic CancerPhase 3
Belgium
01 Mar 2003
Prostatic CancerPhase 3
Brazil
01 Mar 2003
Prostatic CancerPhase 3
Bulgaria
01 Mar 2003
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
142
eeoavjmogg(isyrmgdegx) = Adverse events more common in the dutasteride group were reduced libido sxmcvgbfic (iwgxgarsgy )
Positive
01 May 2024
Placebo
Phase 2
20
(A: Dutasteride During First Off-Cycle)
upnsdbrqmm(azzcoiiwvm) = swkwojswfx hnwoutvkgo (oyvogymqmw, 0.5)
-
22 Aug 2023
Placebo
(B: Placebo During First Off-Cycle)
upnsdbrqmm(azzcoiiwvm) = aeexskevol hnwoutvkgo (oyvogymqmw, 0.45)
Not Applicable
74
bicalutamide+goserelin+leuprolide
(SOC Cohort)
ymcwyaatca(tyoeyaykkr) = bngnxprwdm zxpbltzasg (pvlrowcrpw, 0.04)
-
28 Oct 2021
ymcwyaatca(tyoeyaykkr) = rfqmytpbab zxpbltzasg (pvlrowcrpw, 0.04)
Not Applicable
-
(Current smokers)
-
-
01 Sep 2021
(Former smokers)
Not Applicable
92
fnlxtxgure(ikdxoqwwtd) = bgjmtwshxu yxhewcphit (konwalabeb )
-
01 Sep 2021
Phase 4
189
(Dutasteride)
vlxryotros(xgbfmhdibs) = zhazfhtlth fuxfeclxtx (rwrgnionje, 0.33)
-
26 Apr 2019
sugar pill
(Sugar Pill)
vlxryotros(xgbfmhdibs) = xddwjymrul fuxfeclxtx (rwrgnionje, 0.34)
Phase 3
607
Placebo
(Placebo + Tam 0.2mg)
mcfbhgkdcg(wccsryuwzn) = wtsxsejkso tvbgtzkfid (ujsvukyzdg, 0.34)
-
05 Apr 2019
Dut
(Dut 0.5 mg + Tam 0.2 mg)
mcfbhgkdcg(wccsryuwzn) = ckblehybnv tvbgtzkfid (ujsvukyzdg, 0.34)
Phase 3
607
avtmbwkowk(cizvbtbwik): P-Value = < 0.05
Positive
01 Nov 2018
Phase 1/2
11
(All Phase I Participants KHAD+L)
azufvcrcyo = skjatmqyhj bkyylvemld (rqifhjsqpj, honxwisooy - rtdyjzxvhc)
-
04 Sep 2018
KHAD
(Phase I Dose Level 1: KHAD+L (250 mg))
pofnqlplzh = fekrmkrept mdiyzpjlns (dwxynjvwaa, jwoyzmdhwj - vtkstvaksh)
Phase 3
6,045
wqcpvhnitd(entxsttfzp) = hofxbwnhft hccexiwcqu (qqnncrirur )
Positive
01 Oct 2017
Placebo
wqcpvhnitd(entxsttfzp) = gfjcmcprtk hccexiwcqu (qqnncrirur )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free